Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | CCNC | P24863 | 2/20 | 0.45 |
| ▸ | CDK8 | P49336 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | IGFBP5 | P24593 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5101954 | 0.80 | ALDH1A1 (0.46) | ALOX15ALDH1A1GPR35KDM4ECSNK2A2 | |
| SCHEMBL297225 | 0.80 | ALOX15 (1.00) | ALOX15ALDH1A1GPR35KDM4ELMNA | |
| SCHEMBL18320554 | 0.78 | KDM4E (0.44) | ALOX15ALDH1A1KDM4EL3MBTL1CSNK2A2 | |
| SCHEMBL5101784 | 0.76 | GPR35 (0.49) | ALOX15GPR35KDM4ECSNK2A2CSNK2B | |
| SCHEMBL5090085 | 0.76 | CSNK2A2 (0.40) | ALOX15ALDH1A1KDM4ECSNK2A2CSNK2B | |
| SCHEMBL24985999 | 0.76 | MAOA (0.53) | ALOX15ALDH1A1MAOAKDM4EL3MBTL1 | |
| SCHEMBL23717025 | 0.74 | MAOA (0.46) | ALOX15ALDH1A1MAOACCNCCDK8 | |
| SCHEMBL31254288 | 0.73 | ALOX15 (0.39) | ALOX15ALDH1A1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL5101931 | 0.73 | MAOA (0.42) | ALOX15ALDH1A1MAOAKDM4EL3MBTL1 | |
| SCHEMBL30421051 | 0.72 | ALOX15 (0.64) | ALOX15ALDH1A1GPR35KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207677-A1 | Napthyridine Compounds As Rock Inhibitors | GPC BIOTECH AG (DE) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207677-A1 | Napthyridine Compounds As Rock Inhibitors | ROCK2, ROCK1, RHOT2 | ALOX15 2632/4885ALDH1A1 4506/4885GPR35 419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.