Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.44 |
| ▸ | PGR | P06401 | 5/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 2/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31261247 | 0.79 | CYP11B1 (0.51) | CYP11B1CYP11B2PGRNR3C2PDE3B | |
| SCHEMBL6606966 | 0.72 | PDE3B (0.56) | CYP11B1CYP11B2PGRPDE3BPDE3A | |
| SCHEMBL19187758 | 0.71 | CYP11B1 (0.60) | CYP11B1CYP11B2PGRPDE3BPDE3A | |
| SCHEMBL26654693 | 0.70 | HTR2A (0.44) | CYP11B1CYP11B2 | |
| SCHEMBL26463429 | 0.68 | CYP11B1 (0.64) | CYP11B1CYP11B2PDE3BPDE3AABL1 | |
| SCHEMBL30494231 | 0.68 | CYP11B1 (0.64) | CYP11B1CYP11B2PDE3BPDE3AABL1 | |
| SCHEMBL4596312 | 0.68 | KIF11 (0.63) | CYP11B1CYP11B2PDE3BPDE3ATDP2 | |
| SCHEMBL1897771 | 0.68 | TDP2 (0.75) | CYP11B1CYP11B2PGRPDE3BPDE3A | |
| SCHEMBL24726055 | 0.68 | CYP11B1 (0.50) | CYP11B1CYP11B2PDE3BPDE3ACREBBP | |
| SCHEMBL10915997 | 0.67 | CYP3A4 (0.44) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004272-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2008-01-03 | — | — | US | disclosed |
| US-20080004272-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2008-01-03 | — | — | US | disclosed |
| US-20080004272-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004272-A1 | Compositions and methods for modulating gated ion channels | KCNN3, KCNN2, HCN3 | CYP11B1 4610/4885CYP11B2 4446/4885NR3C1 3957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.