Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.72 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.72 |
| ▸ | ITGAV | P06756 | 1/20 | 0.72 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.72 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11718228 | 0.82 | KDM4E (0.56) | ITGB3ITGB1ITGAVITGA5ITGA4 | |
| SCHEMBL4186674 | 0.81 | KMT2A (0.76) | ITGB3ITGB1ITGAVITGA5ITGA4 | |
| SCHEMBL16098803 | 0.81 | ITGB3 (0.58) | ITGB3ITGB1ITGAVITGA5ITGA4 | |
| SCHEMBL16098801 | 0.81 | ITGB3 (0.58) | ITGB3ITGB1ITGAVITGA5ITGA4 | |
| SCHEMBL16099403 | 0.81 | ITGB3 (0.67) | ITGB3ITGB1ITGAVITGA5ITGA4 | |
| SCHEMBL16099401 | 0.81 | ITGB3 (0.67) | ITGB3ITGB1ITGAVITGA5ITGA4 | |
| SCHEMBL16099910 | 0.80 | KMT2A (0.56) | ITGB3ITGB1ITGAVITGA5ITGA4 | |
| SCHEMBL16099911 | 0.80 | KMT2A (0.56) | ITGB3ITGB1ITGAVITGA5ITGA4 | |
| SCHEMBL11720348 | 0.80 | ALDH1A1 (0.51) | ITGB3ITGB1ITGAVITGA5ITGA4 | |
| SCHEMBL16105032 | 0.80 | ITGB3 (0.70) | ITGB3ITGB1ITGAVITGA5ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7407972-B2 | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade | PFIZER INC. (US) | 2008-08-05 | — | — | US | disclosed |
| US-20060264626-A1 | INHIBITORS OF FACTOR Xa AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | WARNER-LAMBERT COMPANY LLC | 2006-11-23 | — | — | US | disclosed |
| US-20050267118-A1 | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade | WARNER-LAMBERT COMPANY LLC | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267118-A1 | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade | F12, TFPI, F11 | ITGB3 1554/4885ITGB1 1104/4885ITGAV 1610/4885 |
| US-20060264626-A1 | INHIBITORS OF FACTOR Xa AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | F11, F2, TFPI | ITGB3 1313/4885ITGB1 752/4885ITGAV 1727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.