SCHEMBL51054

SCHEMBL51054

CC(c1ccc(-c2ccccc2)cc1O)c1ccc(-c2ccccc2)cc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.57
TYR P14679 1/20 0.55
ACMSD Q8TDX5 3/20 0.48
HNF4A P41235 2/20 0.48
ESR2 Q92731 3/20 0.47
KDM4E B2RXH2 2/20 0.47
MEN1 O00255 1/20 0.47
USP2 O75604 1/20 0.47
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
HSP90AA1 P07900 1/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
ALOX12 P18054 1/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 1/20 0.47
HSD17B10 Q99714 1/20 0.47
DHFR P00374 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17878569 0.88 ALOX5 (0.57) ALOX5TYRACMSDHNF4AESR2
SCHEMBL51794 0.84 ALOX5 (0.57) ALOX5TYRACMSDHNF4AESR2
SCHEMBL27332946 0.82 PTGS2 (0.58) ALOX5ACMSDHNF4AKDM4EGAA
SCHEMBL51614 0.78 ALOX5 (0.55) ALOX5TYRACMSDHNF4AESR2
SCHEMBL4596009 0.78 ALOX5 (0.50) ALOX5ACMSDHNF4AESR2KDM4E
SCHEMBL16528005 0.76 LMNA (0.64) ALOX5TYRLMNAHSP90AA1HPGD
SCHEMBL8714891 0.76 ALOX5 (0.57) ALOX5ACMSDHNF4AESR2KDM4E
SCHEMBL11839204 0.76 ACMSD (0.53) ALOX5ACMSDHNF4AESR2KDM4E
SCHEMBL11850834 0.74 ACMSD (0.51) ALOX5ACMSDHNF4AESR2KDM4E
SCHEMBL4948052 0.74 ACMSD (0.47) ALOX5ACMSDHNF4AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2181853-B1 Thermosensitive recording medium JUJO PAPER CO LTD (JP) 2015-09-23 EP disclosed
US-8492308-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2013-07-23 US disclosed
US-8129307-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2012-03-06 US disclosed
US-20110269622-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2011-11-03 US disclosed
US-20110130281-A1 THERMOSENSITIVE RECORDING MEDIUM API CORPORATION 2011-06-02 US disclosed
EP-2112001-B1 THERMOSENSITIVE RECORDING MEDIUM JUJO PAPER CO LTD (JP) 2011-05-11 EP disclosed
EP-2261045-A1 HEAT-SENSITIVE RECORDING MEDIUM Nippon Paper Industries Co., Ltd. (JP) 2010-12-15 EP disclosed
EP-2181853-A1 THERMAL RECORDING MATERIAL Nippon Paper Industries Co., Ltd. (JP) 2010-05-05 EP disclosed
US-20100099557-A1 Thermosensitive Recording Medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2010-04-22 US disclosed
US-20040241598-A1 Developer for thermal recording material and thermal recording materials NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2004-12-02 US disclosed
EP-1437231-A1 DEVELOPER FOR THERMAL RECORDING MATERIAL AND THERMAL RECORDING MATERIALS API Corporation (JP) 2004-07-14 EP disclosed