Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL710418 | 0.84 | LMNA (0.56) | ALDH1A1MEN1KMT2APOLBLMNA | |
| SCHEMBL7705115 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2APOLBLMNA | |
| SCHEMBL510548 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2APOLBLMNA | |
| SCHEMBL1289928 | 0.83 | CYP2C9 (0.48) | ALDH1A1MEN1KMT2APOLBLMNA | |
| SCHEMBL10443246 | 0.83 | CRHBP (0.54) | ALDH1A1MEN1KMT2APOLBLMNA | |
| SCHEMBL10443280 | 0.83 | KMT2A (0.43) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL10443324 | 0.83 | KCNQ2 (0.43) | ALDH1A1MEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL31558611 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2APOLBLMNA | |
| Toluene SCHEMBL8901851 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2APOLBLMNA | |
| SCHEMBL10443322 | 0.79 | PTGS1 (0.59) | LMNAAKR1C3AKR1C2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028738-A | Process for producing 2-oxo-3-aromatic carboxylic acid derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0386243-A1 | PLATINUM (II) COMPLEXES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1990-09-12 | — | — | EP | disclosed |