Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.43 |
| ▸ | IP6K1 | Q92551 | 5/20 | 0.38 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.38 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604806 | 0.85 | TYMS (0.38) | KIF11IP6K1IP6K3IP6K2ALDH1A1 | |
| SCHEMBL1584889 | 0.77 | PIM1 (0.56) | CYP2A6ALDH1A1CYP1A2MEN1PRNP | |
| SCHEMBL29505633 | 0.77 | CYP2A6 (0.47) | KIF11CYP2A6IP6K1IP6K3IP6K2 | |
| SCHEMBL1160196 | 0.77 | CYP2A6 (0.47) | KIF11CYP2A6IP6K1IP6K3IP6K2 | |
| SCHEMBL8622177 | 0.77 | ACVR1 (0.46) | IP6K1ALDH1A1MEN1PRNPMAPT | |
| SCHEMBL216175 | 0.75 | PARP1 (0.54) | ALDH1A1MEN1PRNPMAPTHPGD | |
| SCHEMBL2191063 | 0.75 | PARP1 (0.54) | ALDH1A1CYP2C19HTTKMT2ACHEK1 | |
| SCHEMBL1507612 | 0.75 | PARP1 (0.54) | ALDH1A1MEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL2574527 | 0.75 | LMNA (0.57) | ALDH1A1CYP1A2MEN1MAPTHPGD | |
| SCHEMBL2191001 | 0.75 | PARP1 (0.54) | ALDH1A1CYP1A2HPGDCHEK1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080261974-A1 | Novel Chemical Compounds | DUFFY KEVIN J | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261974-A1 | Novel Chemical Compounds | HIPK3, HIPK1, HIPK4 | KIF11 808/4885CYP2A6 4760/4885IP6K1 490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.