Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 4/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.41 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.41 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17474576 | 0.85 | SLC6A1 (0.42) | SLC6A1GABRA5GABRB2SLC6A11SLC6A13 | |
| Hydrochloric Acid SCHEMBL25225049 | 0.83 | SLC6A1 (0.41) | SLC6A1GABRA5GABRB2SLC6A11SLC6A13 | |
| SCHEMBL6679121 | 0.82 | MEN1 (0.36) | GABRR1SLC1A2TSHRLMNAMAPK1 | |
| SCHEMBL29017754 | 0.82 | MEN1 (0.36) | GABRR1SLC1A2TSHRLMNAMAPK1 | |
| SCHEMBL20848235 | 0.82 | MEN1 (0.36) | GABRR1SLC1A2TSHRLMNAMAPK1 | |
| SCHEMBL1934562 | 0.82 | MEN1 (0.36) | GABRR1SLC1A2TSHRLMNAMAPK1 | |
| SCHEMBL6679135 | 0.82 | MEN1 (0.36) | GABRR1SLC1A2TSHRLMNAMAPK1 | |
| SCHEMBL12616436 | 0.82 | MEN1 (0.36) | GABRR1SLC1A2TSHRLMNAMAPK1 | |
| SCHEMBL3259610 | 0.81 | ALOX5 (0.42) | SLC6A1GABRA5GABRB2SLC6A11SLC6A13 | |
| Hydrochloric Acid SCHEMBL16667769 | 0.80 | MEN1 (0.35) | GABRR1SLC1A2TSHRLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064704-A1 | 1,4-Diaryl-Dihydropyrimidin-2-Ones and Their Use as Human Neutrophil Elastase Inhibitors | BAYER HEALTHCARE AG (DE) | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064704-A1 | 1,4-Diaryl-Dihydropyrimidin-2-Ones and Their Use as Human Neutrophil Elastase Inhibitors | SERPINB1, ELANE, MPO | SLC6A1 4855/4885GABRA5 4443/4885GABRB2 4571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.