Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5109954 | 1.00 | MAPT (0.35) | MAPTMEN1KMT2AAKT1TLR4 | |
| SCHEMBL2778461 | 0.84 | KMT2A (0.36) | MEN1KMT2ATLR4CYP3A4 | |
| SCHEMBL29487577 | 0.83 | AKT1 (0.31) | AKT1TLR4 | |
| SCHEMBL6565868 | 0.81 | ABCB1 (0.32) | MEN1KMT2APDE10A | |
| SCHEMBL29567882 | 0.80 | TLR4 (0.35) | TLR4PDE10A | |
| SCHEMBL2905278 | 0.80 | TLR4 (0.35) | TLR4PDE10A | |
| SCHEMBL1269359 | 0.80 | TLR4 (0.35) | TLR4PDE10A | |
| Bromide SCHEMBL2910934 | 0.79 | TLR4 (0.34) | TLR4PDE10A | |
| Hydrochloric Acid SCHEMBL2912744 | 0.79 | TLR4 (0.34) | TLR4PDE10A | |
| Hydrochloric Acid SCHEMBL4821106 | 0.76 | BCHE (0.31) | MAPTTLR4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7420070-B2 | Process for preparing optically active 2,3-dihydrobenzofuran compounds | TAKODA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-02 | — | — | US | claimed |
| US-20050171184-A1 | Process for preparing optically active 2,3-dihydrobenzofuran compounds | AOKI ISAO (JP) | 2005-08-04 | — | — | US | claimed |
| US-20050118202-A1 | Solid compositions containing compounds unstable to oxygen and method for stabilization thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-06-02 | — | — | US | claimed |
| EP-1457207-A1 | SOLID COMPOSITIONS CONTAINNG COMPOUNDS UNSTABLE TO OXYGEN AND METHOD FOR STABILIZATION THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2004-09-15 | — | — | EP | claimed |
| US-20040077712-A1 | Process for preparing optically active 2,3-dihydrobenzofuran compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-04-22 | — | — | US | claimed |
| EP-1346988-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 2,3-DIHYDRO- BENZOFURAN COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2003-09-24 | — | — | EP | claimed |
| US-7420070-B2 | Process for preparing optically active 2,3-dihydrobenzofuran compounds | TAKODA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-02 | — | — | US | disclosed |
| US-20050171184-A1 | Process for preparing optically active 2,3-dihydrobenzofuran compounds | AOKI ISAO (JP) | 2005-08-04 | — | — | US | disclosed |
| US-20050118202-A1 | Solid compositions containing compounds unstable to oxygen and method for stabilization thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-06-02 | — | — | US | disclosed |
| US-6878831-B2 | Process for preparing optically active 2,3-dihydrobenzofuran compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-04-12 | — | — | US | disclosed |
| EP-1457207-A1 | SOLID COMPOSITIONS CONTAINNG COMPOUNDS UNSTABLE TO OXYGEN AND METHOD FOR STABILIZATION THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-20040077712-A1 | Process for preparing optically active 2,3-dihydrobenzofuran compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-04-22 | — | — | US | disclosed |
| EP-1346988-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 2,3-DIHYDRO- BENZOFURAN COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2003-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171184-A1 | Process for preparing optically active 2,3-dihydrobenzofuran compounds | ALDH1A2, DHPS, DHODH | MAPT 465/4885MEN1 1951/4885KMT2A 3056/4885 |
| US-20050118202-A1 | Solid compositions containing compounds unstable to oxygen and method for stabilization thereof | SCO2, PROC, TTPA | MAPT 1995/4885MEN1 1620/4885KMT2A 1916/4885 |
| US-20040077712-A1 | Process for preparing optically active 2,3-dihydrobenzofuran compounds | ALDH1A2, PARK7, DHPS | MAPT 392/4885MEN1 2199/4885KMT2A 3019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.