Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12316609 | 0.96 | GPR119 (0.55) | GPR119ABL1SMN1; SMN2HPGDTP53 | |
| SCHEMBL7798265 | 0.81 | ABL1 (0.44) | GPR119ABL1SMN1; SMN2HPGDTP53 | |
| SCHEMBL11904439 | 0.75 | GPR119 (0.53) | GPR119SMN1; SMN2HPGDRAB9AALDH1A1 | |
| SCHEMBL5728560 | 0.75 | GPR119 (0.51) | GPR119ABL1CASP1HSD17B10CHEK1 | |
| SCHEMBL86224 | 0.75 | MAOB (0.45) | MAOBMAOA | |
| SCHEMBL14149928 | 0.74 | MAPT (0.59) | SMN1; SMN2HPGDTP53RAB9AALDH1A1 | |
| SCHEMBL16976374 | 0.74 | MAOB (0.50) | GPR119SMN1; SMN2HPGDRAB9AALDH1A1 | |
| SCHEMBL11112325 | 0.73 | AKT1 (0.49) | ABL1HPGDALDH1A1MAPTMEN1 | |
| SCHEMBL11365987 | 0.73 | MAPT (0.54) | ABL1SMN1; SMN2HPGDTP53RAB9A | |
| SCHEMBL12316616 | 0.72 | CYP1A2 (0.63) | GPR119SMN1; SMN2HPGDRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080103307-A1 | Chroman Compound, Processes for Its Preparation, and Its Pharmaceutical Use | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2008-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103307-A1 | Chroman Compound, Processes for Its Preparation, and Its Pharmaceutical Use | KCNH1, HCN4, HCN1 | GPR119 3321/4885ABL1 699/4885SMN1; SMN2 2182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.