Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.34 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.34 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.34 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5112370 | 0.90 | FFAR1 (0.39) | FFAR1KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL5104161 | 0.89 | KMT2A (0.39) | TACR1FFAR1KMT2AMEN1SLC7A5 | |
| SCHEMBL5112161 | 0.89 | ALDH1A1 (0.38) | TACR1FFAR1KMT2AMEN1MAPK1 | |
| SCHEMBL5116750 | 0.89 | THRB (0.42) | TACR1FFAR1KMT2AMEN1SLC7A5 | |
| SCHEMBL4935426 | 0.89 | FFAR1 (0.39) | TACR1FFAR1KMT2AMEN1SLC7A5 | |
| SCHEMBL4931768 | 0.89 | FFAR1 (0.40) | TACR1FFAR1KMT2ASLC7A5MRGPRX4 | |
| SCHEMBL4931582 | 0.87 | FFAR1 (0.39) | TACR1FFAR1KMT2AMEN1SLC7A5 | |
| SCHEMBL5110521 | 0.86 | MRGPRX4 (0.39) | FFAR1MRGPRX4RORCPTGER1 | |
| SCHEMBL4932666 | 0.86 | FFAR1 (0.38) | TACR1FFAR1KMT2AMEN1SLC7A5 | |
| SCHEMBL5722645 | 0.86 | FFAR1 (0.37) | FFAR1KMT2AMEN1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004251-A1 | Novel Pharmaceutical Compositions Comprising Agonists of the Thyroid Receptor | KARO BIO AB (SE) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004251-A1 | Novel Pharmaceutical Compositions Comprising Agonists of the Thyroid Receptor | TSHR, TRHR, THRA | TACR1 81/4885FFAR1 34/4885KMT2A 2895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.