SCHEMBL5116750

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5722653	0.92	THRA (0.41)	THRBTHRADHODHFFAR1PTGER1
	SCHEMBL5111457	0.89	THRB (0.40)	THRBTHRADHODHFFAR1KMT2A
	SCHEMBL5110048	0.89	THRA (0.40)	THRBTHRADHODHFFAR1MEN1
	SCHEMBL5110197	0.89	TACR1 (0.40)	FFAR1MEN1KMT2ASLC7A5TACR1
	SCHEMBL4934394	0.89	THRB (0.42)	THRBTHRADHODHFFAR1MEN1
	SCHEMBL4349711	0.89	THRB (0.40)	THRBTHRADHODHFFAR1PTGER1
	SCHEMBL4926936	0.89	THRB (0.43)	THRBTHRAFFAR1SLC7A5ESR1
	SCHEMBL4922928	0.87	THRB (0.50)	THRBTHRAFFAR1ESR1NR3C1
	SCHEMBL5112643	0.86	THRA (0.44)	THRBTHRADHODHTACR1PTGER1
	SCHEMBL4931744	0.86	THRB (0.42)	THRBTHRAFFAR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.