Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 3/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 5/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721464 | 0.93 | ELANE (0.39) | UTS2RELANEFAAHHTTCES1 | |
| SCHEMBL4721466 | 0.89 | ELANE (0.38) | UTS2RELANEFAAHHTTCES1 | |
| SCHEMBL5101056 | 0.89 | HCAR3 (0.33) | CRHR1HTT | |
| SCHEMBL4721756 | 0.85 | GBA1 (0.35) | ELANEHTTSMN1; SMN2 | |
| SCHEMBL4724016 | 0.81 | HCAR3 (0.35) | CRHR1FAAHHTTCES1MAPT | |
| SCHEMBL4723841 | 0.80 | HRH3 (0.36) | UTS2RFAAHCES1KDM4EALDH1A1 | |
| SCHEMBL4724154 | 0.72 | HCAR3 (0.37) | KDM4EALDH1A1MAPT | |
| SCHEMBL16316871 | 0.71 | CRHR1 (0.44) | UTS2RELANECRHR1HTTKDM4E | |
| SCHEMBL11527629 | 0.70 | MLYCD (0.45) | ELANEFAAHCES1ALDH1A1 | |
| SCHEMBL30088772 | 0.67 | ALDH1A1 (0.43) | FAAHCES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176857-A1 | 4-Piperazinnylthieno[2,3-d]Pyrimidine Compounds as Platelet Aggregation Inhibitors | PFIZER INC. | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176857-A1 | 4-Piperazinnylthieno[2,3-d]Pyrimidine Compounds as Platelet Aggregation Inhibitors | TBXA2R, P2RY4, PF4 | UTS2R 632/4885ELANE 2494/4885CRHR1 3095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.