Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5114575 | 0.89 | CYSLTR1 (0.45) | CYSLTR1GPBAR1CYSLTR2PTGDR2MEN1 | |
| SCHEMBL5120280 | 0.83 | CYSLTR1 (0.50) | CYSLTR1GPBAR1CYSLTR2PTGDR2MEN1 | |
| SCHEMBL5105338 | 0.83 | CYP1A2 (0.40) | CYSLTR1GPBAR1CYSLTR2PTGDR2TLR8 | |
| SCHEMBL5110602 | 0.82 | GPBAR1 (0.48) | CYSLTR1GPBAR1CYSLTR2MEN1KMT2A | |
| SCHEMBL5106908 | 0.81 | CYSLTR1 (0.46) | CYSLTR1GPBAR1CYSLTR2PTGDR2MEN1 | |
| SCHEMBL5109059 | 0.79 | POLB (0.41) | MAPTMAPK1TP53CYP1A2ALDH1A1 | |
| SCHEMBL5112554 | 0.79 | PTGDR2 (0.43) | CYSLTR1GPBAR1CYSLTR2PTGDR2AKR1B1 | |
| SCHEMBL5121992 | 0.75 | PPARG (0.55) | CYSLTR1GPBAR1CYSLTR2PTGDR2AKR1B1 | |
| SCHEMBL5120863 | 0.73 | PPARG (0.40) | CYSLTR1GPBAR1CYSLTR2PTGDR2AKR1B1 | |
| SCHEMBL30060467 | 0.72 | MEN1 (0.61) | CYSLTR1GPBAR1CYSLTR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-02-28 | — | — | US | disclosed |
| EP-1829863-A1 | ARYLALKANOIC ACID DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2007-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | INSR, NPY1R, GPR119 | CYSLTR1 806/4885GPBAR1 252/4885CYSLTR2 1286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.