Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.50 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5109080 | 0.87 | CYSLTR2 (0.46) | CYSLTR1CYSLTR2PTGDR2MEN1PRNP | |
| SCHEMBL5114575 | 0.83 | CYSLTR1 (0.45) | CYSLTR1CYSLTR2GPBAR1PTGDR2MEN1 | |
| SCHEMBL5105836 | 0.83 | ALDH1A1 (0.47) | MAPTPPARGALDH1A1LMNA | |
| SCHEMBL5113694 | 0.83 | CYSLTR1 (0.48) | CYSLTR1CYSLTR2GPBAR1PTGDR2MEN1 | |
| SCHEMBL5120054 | 0.79 | KDM4E (0.44) | MEN1KMT2AMAPTPPARGKDM4E | |
| SCHEMBL5113810 | 0.78 | PPARG (0.47) | MAPTPPARGKDM4EALDH1A1LMNA | |
| SCHEMBL5109743 | 0.77 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2GPBAR1PPARGPPARD | |
| SCHEMBL5106908 | 0.77 | CYSLTR1 (0.46) | CYSLTR1CYSLTR2GPBAR1PTGDR2MEN1 | |
| SCHEMBL5112554 | 0.75 | PTGDR2 (0.43) | CYSLTR1CYSLTR2GPBAR1PTGDR2PPARG | |
| SCHEMBL5120832 | 0.75 | ALDH1A1 (0.44) | PTGDR2PPARGKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-02-28 | — | — | US | disclosed |
| EP-1829863-A1 | ARYLALKANOIC ACID DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2007-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | INSR, NPY1R, GPR119 | CYSLTR1 806/4885CYSLTR2 1286/4885GPBAR1 252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.