Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5113694 | 0.89 | CYSLTR1 (0.48) | CYSLTR1GPBAR1CYSLTR2PDE10APTGDR2 | |
| SCHEMBL5120863 | 0.84 | PPARG (0.40) | CYSLTR1GPBAR1CYSLTR2PDE10APTGDR2 | |
| SCHEMBL5120280 | 0.83 | CYSLTR1 (0.50) | CYSLTR1GPBAR1CYSLTR2PTGDR2MEN1 | |
| SCHEMBL5110194 | 0.81 | CYP11B1 (0.43) | CYP1A2TP53ALDH1A1LMNAHPGD | |
| SCHEMBL5121992 | 0.79 | PPARG (0.55) | CYSLTR1GPBAR1CYSLTR2PDE10APTGDR2 | |
| SCHEMBL5106908 | 0.77 | CYSLTR1 (0.46) | CYSLTR1GPBAR1CYSLTR2PTGDR2MEN1 | |
| SCHEMBL5111033 | 0.77 | PPARG (0.43) | MEN1KMT2ACYP2C19ALDH1A1LMNA | |
| SCHEMBL5121178 | 0.76 | PPARG (0.46) | ALDH1A1NPSR1MAPTPPARG | |
| SCHEMBL5112554 | 0.75 | PTGDR2 (0.43) | CYSLTR1GPBAR1CYSLTR2PTGDR2ALOX5 | |
| SCHEMBL5111910 | 0.74 | CYSLTR1 (0.43) | CYSLTR1GPBAR1CYSLTR2MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-02-28 | — | — | US | disclosed |
| EP-1829863-A1 | ARYLALKANOIC ACID DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2007-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051418-A1 | Arylalkanoic Acid Derivative | INSR, NPY1R, GPR119 | CYSLTR1 806/4885GPBAR1 252/4885CYSLTR2 1286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.