Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MDH2 | P40926 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 4/20 | 0.56 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTR1D | P28221 | 3/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | KIF20A | O95235 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023222 | 0.87 | NR4A2 (0.66) | POLBALDH1A1HPGDMDH2SMN1; SMN2 | |
| SCHEMBL6764594 | 0.86 | MAOB (0.61) | POLBALDH1A1HPGDMDH2SMN1; SMN2 | |
| SCHEMBL6098744 | 0.85 | ALDH1A1 (0.57) | POLBALDH1A1HPGDMDH2SMN1; SMN2 | |
| SCHEMBL28123392 | 0.84 | TRPM8 (0.60) | POLBALDH1A1HPGDMDH2SMN1; SMN2 | |
| SCHEMBL7376780 | 0.84 | ALDH1A1 (0.59) | POLBALDH1A1HPGDMDH2SMN1; SMN2 | |
| SCHEMBL11602121 | 0.84 | ALDH1A1 (0.61) | POLBALDH1A1HPGDMDH2SMN1; SMN2 | |
| SCHEMBL18549394 | 0.84 | LTA4H (0.63) | POLBALDH1A1HPGDMDH2SMN1; SMN2 | |
| SCHEMBL6826445 | 0.83 | ALDH1A1 (0.60) | POLBALDH1A1HPGDMDH2SMN1; SMN2 | |
| SCHEMBL7382353 | 0.83 | MEN1 (0.64) | POLBALDH1A1HPGDMDH2SMN1; SMN2 | |
| SCHEMBL4030619 | 0.82 | TRPM8 (0.63) | POLBALDH1A1HPGDMDH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7468380-B2 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-12-23 | — | — | US | disclosed |
| US-20070004764-A1 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-01-04 | — | — | US | disclosed |
| US-7109219-B2 | Nitrogen-containing aromatic derivatives | EISAI CO., LTD. (JP) | 2006-09-19 | — | — | US | disclosed |
| US-20060004029-A1 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2006-01-05 | — | — | US | disclosed |
| US-20050187236-A1 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-08-25 | — | — | US | disclosed |
| EP-1522540-A1 | AZAARENE DERIVATIVES | Eisai Co., Ltd. (JP) | 2005-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004029-A1 | Nitrogen-containing aromatic derivatives | NR0B2, NR0B1, NR4A1 | POLB 2891/4885ALDH1A1 1501/4885HPGD 2778/4885 |
| US-20050187236-A1 | Nitrogen-containing aromatic derivatives | NR0B2, NR0B1, NR4A1 | POLB 2891/4885ALDH1A1 1501/4885HPGD 2778/4885 |
| US-20070004764-A1 | Nitrogen-containing aromatic derivatives | NR0B2, NR0B1, NR4A1 | POLB 2891/4885ALDH1A1 1501/4885HPGD 2778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.