Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 10/20 | 0.53 |
| ▸ | AVPR1B | P47901 | 5/20 | 0.53 |
| ▸ | AVPR2 | P30518 | 10/20 | 0.51 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 5/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985203 | 0.81 | AVPR1A (0.61) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL4146200 | 0.79 | AVPR1A (0.68) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6989910 | 0.78 | AVPR1A (0.46) | AVPR1AAVPR1BAVPR2SMN1; SMN2 | |
| SCHEMBL6991806 | 0.77 | AVPR1A (0.47) | AVPR1AAVPR1BAVPR2SMN1; SMN2 | |
| SCHEMBL5235720 | 0.77 | AVPR1A (0.53) | AVPR1AAVPR1BAVPR2SMN1; SMN2 | |
| SCHEMBL7093443 | 0.73 | ALDH1A1 (0.58) | AVPR1AAVPR1BAVPR2OXTRSMN1; SMN2 | |
| SCHEMBL19217285 | 0.72 | HPGD (0.69) | SLC6A7 | |
| SCHEMBL6203310 | 0.72 | AVPR1A (0.60) | AVPR1AAVPR1BAVPR2OXTR | |
| SCHEMBL6990010 | 0.72 | AVPR1A (0.59) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6988048 | 0.71 | NAAA (0.55) | AVPR1AAVPR1BAVPR2SLC6A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183734-A1 | Cyclohexylphenyl vasopressin agonists | WYETH (US) | 2006-08-17 | — | — | US | claimed |
| EP-1381608-A1 | CYCLOHEXYLPHENYL VASOPRESSIN AGONISTS | Wyeth (US) | 2004-01-21 | — | — | EP | claimed |
| US-20020198191-A1 | Medicine for inducing temporary delay of urination or treatment of disorders of diabetes insipidus, nocturnal enuresis, nocturia, urinary incontinence, or bleeding and coagulation disorders | WYETH (US) | 2002-12-26 | — | — | US | claimed |
| WO-2002083685-A1 | CYCLOHEXYLPHENYL VASOPRESSIN AGONISTS | WYETH (US) | 2002-10-24 | — | — | WO | claimed |
| US-7329653-B2 | Cyclohexylphenyl vasopressin agonists | WYETH (US) | 2008-02-12 | — | — | US | disclosed |
| US-20060183734-A1 | Cyclohexylphenyl vasopressin agonists | WYETH (US) | 2006-08-17 | — | — | US | disclosed |
| US-7053083-B2 | Cyclohexylphenyl vasopressin agonists | WYETH (US) | 2006-05-30 | — | — | US | disclosed |
| EP-1381608-A1 | CYCLOHEXYLPHENYL VASOPRESSIN AGONISTS | Wyeth (US) | 2004-01-21 | — | — | EP | disclosed |
| US-20020198191-A1 | Medicine for inducing temporary delay of urination or treatment of disorders of diabetes insipidus, nocturnal enuresis, nocturia, urinary incontinence, or bleeding and coagulation disorders | WYETH (US) | 2002-12-26 | — | — | US | disclosed |
| WO-2002083685-A1 | CYCLOHEXYLPHENYL VASOPRESSIN AGONISTS | WYETH (US) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020198191-A1 | Medicine for inducing temporary delay of urination or treatment of disorders of diabetes insipidus, nocturnal enuresis, nocturia, urinary incontinence, or bleeding and coagulation disorders | F2, AVPR2, SHBG | AVPR1A 6/4885AVPR1B 5/4885AVPR2 2/4885 |
| US-20060183734-A1 | Cyclohexylphenyl vasopressin agonists | AVPR2, AVPR1A, AVPR1B | AVPR1A 2/4885AVPR1B 3/4885AVPR2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.