Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.60 |
| ▸ | MAOB | P27338 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | PPARA | Q07869 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5123020 | 0.90 | SLC16A3 (0.67) | MAOBMEN1NPC1POLBMAPT | |
| SCHEMBL5109572 | 0.81 | MAOB (0.80) | MAOAMAOBPPARGPPARA | |
| SCHEMBL7900907 | 0.81 | PTGS1 (0.54) | MEN1NPC1POLBMAPTRAB9A | |
| SCHEMBL17704677 | 0.77 | MAOB (0.66) | MAOAMAOBNPC1PPARGPPARA | |
| SCHEMBL6516526 | 0.77 | GPR84 (0.61) | MEN1NPC1POLBMAPTRAB9A | |
| SCHEMBL7911142 | 0.76 | MTNR1A (0.53) | MAOAMAOBMEN1POLBMAPT | |
| SCHEMBL24176813 | 0.75 | MAOB (0.76) | MAOAMAOBMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7340338 | 0.75 | MAOB (1.00) | MAOAMAOBMAPTPPARGPPARA | |
| SCHEMBL93418 | 0.75 | MAOB (0.80) | MAOAMAOB | |
| SCHEMBL27750409 | 0.75 | MAOB (1.00) | MAOAMAOBMAPTPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060178405-A1 | Benzopyran compounds, process for preparing the same and their use | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2006-08-10 | — | — | US | claimed |
| EP-1598345-A1 | BENZOPYRAN COMPOUNDS, PROCESS FOR PREPARING THE SAME AND THEIR USE | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2005-11-23 | — | — | EP | claimed |
| US-7456205-B2 | Benzopyran compounds, process for preparing the same and their use | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2008-11-25 | — | — | US | disclosed |
| US-20060178405-A1 | Benzopyran compounds, process for preparing the same and their use | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2006-08-10 | — | — | US | disclosed |
| EP-1598345-A1 | BENZOPYRAN COMPOUNDS, PROCESS FOR PREPARING THE SAME AND THEIR USE | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2005-11-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178405-A1 | Benzopyran compounds, process for preparing the same and their use | SLC5A2, CYP2D6, IAPP | MAOA 1404/4885MAOB 804/4885MEN1 869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.