SCHEMBL5117718

SCHEMBL5117718

Cc1cc([S+](c2ccccc2)c2ccccc2)cc(C)c1O.O=S(=O)([O-])C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYTH2 Q99418 1/20 0.35
TTR P02766 2/20 0.34
ALOX5 P09917 1/20 0.34
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
BRD4 O60885 2/20 0.33
CA1 P00915 7/20 0.32
CA2 P00918 7/20 0.32
MMP1 P03956 4/20 0.32
MMP2 P08253 4/20 0.32
MMP9 P14780 4/20 0.32
MMP8 P22894 4/20 0.32
MMP13 P45452 4/20 0.32
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HSD11B1 P28845 2/20 0.30
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3779513 0.87 HSD17B2 (0.39) BRD4HSD11B1
SCHEMBL3144008 0.85 PTGS1 (0.32) PTGS1PTGS2CA1CA2
SCHEMBL51399 0.85 CA2 (0.38) CA1CA2MMP1MMP2MMP9
SCHEMBL1482705 0.85 CA2 (0.38) CA1CA2MMP1MMP2MMP9
SCHEMBL3139331 0.84 PTGS1 (0.32) PTGS1PTGS2CA1CA2
SCHEMBL3132254 0.84 PTGS1 (0.32) PTGS1PTGS2CA1CA2
SCHEMBL4535202 0.84 CA2 (0.39) CA1CA2MMP1MMP2MMP9
SCHEMBL60437 0.84 CA2 (0.39) CA1CA2MMP1MMP2MMP9
Perflubutane SCHEMBL6325042 0.84 CA2 (0.39) CA1CA2MMP1MMP2MMP9
SCHEMBL546546 0.84 CA2 (0.39) CA1CA2MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7396960-B2 Sulfonium salts TOYO GOSEI CO., LTD. (JP) 2008-07-08 US disclosed
US-20070219368-A1 Sulfonium salts TOYO GOSEI CO., LTD. (JP) 2007-09-20 US disclosed
US-7192685-B2 Positive resist composition and method of forming resist pattern using the same. FUJI PHOTO FILM CO., LTD. (JP) 2007-03-20 US disclosed
US-20040197708-A1 Positive resist composition and method of forming resist pattern using the same FUJI PHOTO FILM CO., LTD. 2004-10-07 US disclosed
EP-1462858-A1 Positive resist composition and method of forming resist pattern using the same Fuji Photo Film Co., Ltd. (JP) 2004-09-29 EP disclosed
US-6358665-B1 ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE CLARIANT INTERNATIONAL LTD. (CH) 2002-03-19 US disclosed
EP-1033624-A1 RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE Clariant International Ltd. (CH) 2000-09-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070219368-A1 Sulfonium salts C1S, F12, C1R CYTH2 3711/4885TTR 3785/4885ALOX5 1832/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.