Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | RHOC | P08134 | 1/20 | 0.40 |
| ▸ | RHOA | P61586 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CLPP | Q16740 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 9/20 | 0.39 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.38 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.38 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | JUN | P05412 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722472 | 0.96 | THRB (0.41) | SCN9ARHOCRHOASMN1; SMN2CLPP | |
| SCHEMBL5111593 | 0.91 | THRA (0.42) | SCN9ARHOCRHOASMN1; SMN2CLPP | |
| SCHEMBL4923555 | 0.89 | MRGPRX4 (0.41) | RHOCRHOAMRGPRX4 | |
| SCHEMBL5104851 | 0.89 | RHOC (0.42) | RHOCRHOAMRGPRX4JUNNFKB1 | |
| SCHEMBL5722474 | 0.88 | SCN9A (0.39) | SCN9ARHOCRHOASMN1; SMN2CLPP | |
| SCHEMBL5103298 | 0.88 | RHOC (0.45) | RHOCRHOAMRGPRX4SENP5SENP2 | |
| SCHEMBL5110128 | 0.87 | SENP5 (0.40) | SMN1; SMN2SENP5SENP2SENP1ALDH1A1 | |
| SCHEMBL4932213 | 0.87 | MRGPRX4 (0.43) | RHOCRHOAMRGPRX4MEN1KMT2A | |
| SCHEMBL5104457 | 0.87 | SENP5 (0.41) | SMN1; SMN2MRGPRX4SENP5SENP2SENP1 | |
| SCHEMBL5117805 | 0.86 | SENP5 (0.40) | SMN1; SMN2SENP5SENP2SENP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004251-A1 | Novel Pharmaceutical Compositions Comprising Agonists of the Thyroid Receptor | KARO BIO AB (SE) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004251-A1 | Novel Pharmaceutical Compositions Comprising Agonists of the Thyroid Receptor | TSHR, TRHR, THRA | SCN9A 1472/4885RHOC 1411/4885RHOA 1679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.