Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.68 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24125059 | 0.93 | MAPT (0.82) | MAPTMCOLN3CA12CA9LMNA | |
| SCHEMBL16211204 | 0.91 | PGR (0.61) | MAPTMCOLN3CA12CA9PGR | |
| SCHEMBL2518894 | 0.90 | CA12 (0.71) | MAPTMCOLN3CA12CA9LMNA | |
| SCHEMBL2008337 | 0.81 | MAPT (1.00) | MAPTMCOLN3CA12CA9LMNA | |
| SCHEMBL519624 | 0.80 | LMNA (0.59) | CA12CA9LMNAALDH1A1CYP3A4 | |
| SCHEMBL25920658 | 0.79 | ALDH1A1 (0.59) | MAPTMCOLN3CA12CA9LMNA | |
| SCHEMBL11764723 | 0.79 | PGR (0.71) | MAPTMCOLN3CA12CA9LMNA | |
| SCHEMBL5623176 | 0.79 | ALDH1A1 (0.71) | MAPTMCOLN3CA12CA9LMNA | |
| SCHEMBL1916178 | 0.78 | ALDH1A1 (0.52) | MAPTMCOLN3CA12CA9LMNA | |
| Hydrochloric Acid SCHEMBL11880596 | 0.78 | LMNA (0.57) | CA12CA9LMNAALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7459585-B2 | Benzene derivatives and pharmaceutical use thereof | AJINOMOTO CO., INC. (JP) | 2008-12-02 | — | — | US | disclosed |
| US-20050165114-A1 | Benzene derivatives and pharmaceutical use thereof | AJINOMOTO CO. INC (JP) | 2005-07-28 | — | — | US | disclosed |
| US-6703379-B2 | ANTIINFLAMMATORY AGENT, IMMUNOSUPPRESSANT, ANTICANCER AGENTS, ANTIARTHRITIC AGENTS | AJINOMOTO CO., INC. (JP) | 2004-03-09 | — | — | US | disclosed |
| US-20030166693-A1 | Benzene derivatives and pharmaceutical use thereof | AJINOMOTO CO., INC (JP) | 2003-09-04 | — | — | US | disclosed |
| US-20010018441-A1 | Benzene derivatives and Pharmaceutical use thereof | AJINOMOTO CO., INC. (JP) | 2001-08-30 | — | — | US | disclosed |
| EP-1113000-A1 | BENZENE DERIVATIVES AND MEDICINAL USE THEREOF | Ajinomoto Co., Inc. (JP) | 2001-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166693-A1 | Benzene derivatives and pharmaceutical use thereof | NFKBIA, VCAM1, NFKB1 | MAPT 2829/4885MCOLN3 4154/4885CA12 2512/4885 |
| US-20050165114-A1 | Benzene derivatives and pharmaceutical use thereof | NFKBIA, VCAM1, NFKB1 | MAPT 2748/4885MCOLN3 4216/4885CA12 2487/4885 |
| US-20010018441-A1 | Benzene derivatives and Pharmaceutical use thereof | NFKBIA, VCAM1, NFKB1 | MAPT 2829/4885MCOLN3 4154/4885CA12 2512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.