Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5128387 | 0.94 | BDKRB1 (0.38) | MEN1KMT2APKMMAPK1JAK2 | |
| SCHEMBL5131253 | 0.87 | CNR1 (0.40) | MEN1KMT2APKMJAK2JAK1 | |
| SCHEMBL5128337 | 0.86 | ALDH1A1 (0.42) | MEN1KMT2APKMMAPK1 | |
| SCHEMBL5128724 | 0.85 | HTR6 (0.38) | EPHX2MEN1KMT2AMAPK1 | |
| SCHEMBL5125291 | 0.83 | GAA (0.43) | MEN1KMT2APKM | |
| SCHEMBL5131323 | 0.83 | HSD17B10 (0.45) | EPHX2MEN1KMT2AMAPK1 | |
| SCHEMBL5122795 | 0.82 | SLC6A9 (0.42) | — | |
| SCHEMBL5128955 | 0.81 | ALDH1A1 (0.45) | PKMMAPK1 | |
| SCHEMBL5131821 | 0.81 | CCR2 (0.48) | KMT2A | |
| SCHEMBL5128076 | 0.81 | ATM (0.46) | MEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | claimed |
| US-8580965-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2013-11-12 | — | — | US | disclosed |
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249128-A1 | Substituted Sulfonamide Compounds | BDKRB1, BDKRB2, NPSR1 | EPHX2 1287/4885EBP 3364/4885DHCR7 3057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.