SCHEMBL5128971 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	MTNR1A	P48039	2/20	0.42

▸	MTNR1B	P49286	2/20	0.42

▸	ALDH1A1	P00352	3/20	0.40

▸	MAPK1	P28482	1/20	0.40

▸	KDM2B	Q8NHM5	9/20	0.39

▸	HSD11B1	P28845	1/20	0.39

▸	MGLL	Q99685	1/20	0.39

▸	PGR	P06401	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3844268	0.92	POLB (0.42)	ALDH1A1MAPK1KDM2B
SCHEMBL3843530	0.90	FFAR1 (0.46)	ALDH1A1MAPK1KDM2BMGLL
SCHEMBL3843546	0.89	HTR2C (0.41)	ALDH1A1MAPK1KDM2B
SCHEMBL3841290	0.89	ALDH1A1 (0.47)	ALDH1A1MAPK1KDM2BMGLL
SCHEMBL3846304	0.88	HTR2C (0.42)	ALDH1A1MAPK1KDM2B
Hydrochloric Acid SCHEMBL3860311	0.88	ALDH1A1 (0.47)	ALDH1A1MAPK1KDM2BMGLL
SCHEMBL3881602	0.86	MEN1 (0.43)	ALDH1A1MAPK1KDM2B
SCHEMBL3846301	0.83	SCN9A (0.41)	ALDH1A1MAPK1KDM2BHSD11B1
SCHEMBL3839546	0.83	KDM4E (0.41)	ALDH1A1MAPK1MGLL
SCHEMBL3862104	0.83	SCN9A (0.41)	ALDH1A1MAPK1KDM2BHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2007136668-A9	N-BENZOYL-AND N-BENZYLPYRROLIDIN-3-YLAMINES AS HISTAMINE-3 ANTAGONISTS	WYETH CORP (US)	2008-03-27	—	—	WO	claimed