Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.40 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.40 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 4/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3841290 | 0.90 | ALDH1A1 (0.47) | FFAR1ALDH1A1HTTMAPK1MGLL | |
| SCHEMBL3844103 | 0.89 | BTK (0.39) | MAPT | |
| SCHEMBL3881602 | 0.89 | MEN1 (0.43) | KDM4EMAPTMEN1KMT2AFFAR1 | |
| SCHEMBL3844268 | 0.89 | POLB (0.42) | KDM4EMAPTATMMEN1KMT2A | |
| SCHEMBL3862104 | 0.89 | SCN9A (0.41) | ALDH1A1MAPK1 | |
| SCHEMBL3846301 | 0.89 | SCN9A (0.41) | ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL3860311 | 0.89 | ALDH1A1 (0.47) | FFAR1ALDH1A1HTTMAPK1MGLL | |
| SCHEMBL5139829 | 0.87 | HTR2C (0.42) | MEN1KMT2AFFAR1HTR2CHTR2B | |
| SCHEMBL5131548 | 0.87 | HTR2C (0.42) | MEN1KMT2AFFAR1HTR2CHTR2B | |
| SCHEMBL5128971 | 0.83 | MTNR1A (0.42) | ALDH1A1MAPK1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027086-A2 | N-BENZOYL-AND N-BENZYLPYRROLIDIN-3-YLAMINES AS HISTAMINE-3 ANTAGONISTS | Wyeth (US) | 2009-02-25 | — | — | EP | claimed |
| WO-2007136668-A9 | N-BENZOYL-AND N-BENZYLPYRROLIDIN-3-YLAMINES AS HISTAMINE-3 ANTAGONISTS | WYETH CORP (US) | 2008-03-27 | — | — | WO | claimed |
| WO-2007136668-A2 | N-BENZOYL-AND N-BENZYLPYRROLIDIN-3-YLAMINES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2007-11-29 | — | — | WO | claimed |