SCHEMBL5129206

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5121054	0.89	ALOX5 (0.55)	ADORA1PIM1AURKBTRIM24ALOX5
	SCHEMBL5117716	0.88	ALOX5 (0.64)	ALOX5ALDH1A1GAAKDM4EGFER
	SCHEMBL5118740	0.88	GAA (0.55)	ADORA1PIM1AURKBTRIM24ALOX5
	SCHEMBL5128462	0.87	ALDH1A1 (0.60)	ADORA1ROCK2PIM1GSK3BAURKB
	SCHEMBL5113404	0.87	TRPA1 (0.60)	ALOX5ALDH1A1GAABACE1
	SCHEMBL5119275	0.86	TRPA1 (0.61)	ALOX5ALDH1A1GAAKDM4EBACE1
	SCHEMBL5129666	0.85	MAPK1 (0.54)	ADORA1ROCK2PIM1GSK3BAURKB
	SCHEMBL13464225	0.83	ADORA1 (0.63)	ADORA1ROCK2PIM1GSK3BAURKB
	SCHEMBL5129211	0.82	TUBB4A (0.50)	ALDH1A1GAAKDM4EGFERMAPT
	SCHEMBL5120431	0.79	ADRA1B (0.47)	ALDH1A1GAAKDM4EGFERMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.