Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 8/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083312 | 0.94 | LTA4H (0.49) | ALDH1A1MAOBAOC3CA1CA2 | |
| SCHEMBL2726596 | 0.82 | CA12 (0.42) | ALDH1A1AOC3CA1CA2CA9 | |
| SCHEMBL27467410 | 0.81 | PPARA (0.40) | ALDH1A1MAOBAOC3CYP1A1CYP1B1 | |
| SCHEMBL15756604 | 0.81 | PPARA (0.47) | ALDH1A1MAOBAOC3CYP1A1CYP1B1 | |
| Formic Acid SCHEMBL15743043 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MAOBAOC3CA1CA2 | |
| SCHEMBL8341924 | 0.80 | PPARA (0.39) | ALDH1A1CYP1A1CYP1B1PPARAMRGPRX4 | |
| SCHEMBL1822846 | 0.80 | SMN1; SMN2 (0.55) | ALDH1A1MAOBAOC3CA1CA2 | |
| SCHEMBL514625 | 0.80 | MAOB (0.47) | ALDH1A1MAOBAOC3PPARAMRGPRX4 | |
| SCHEMBL1400474 | 0.80 | CA12 (0.49) | ALDH1A1MAOBAOC3CA1CA2 | |
| SCHEMBL7263140 | 0.80 | ALDH1A1 (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023210623-A1 | HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME | 株式会社エス・ディー・エス バイオテック | 2023-11-02 | — | — | WO | disclosed |
| CN-110143932-B | Piperazinone derivatives, process for producing the same, inhibitor, and method for controlling root-parasitic weeds | 南开大学 | 2022-09-16 | — | — | CN | disclosed |
| US-11161824-B2 | Heterocyclic lipoxin analogs and uses thereof | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2021-11-02 | — | — | US | disclosed |
| US-11161824-B2 | Heterocyclic lipoxin analogs and uses thereof | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2021-11-02 | — | — | US | disclosed |
| EP-3500559-B1 | HETEROCYCLIC LIPOXIN ANALOGS AND USES THEROF | UNIV COLLEGE DUBLIN NAT UNIV IRELAND DUBLIN (IE) | 2021-06-16 | — | — | EP | disclosed |
| EP-3500559-B1 | HETEROCYCLIC LIPOXIN ANALOGS AND USES THEROF | UNIV COLLEGE DUBLIN NAT UNIV IRELAND DUBLIN (IE) | 2021-06-16 | — | — | EP | disclosed |
| US-20210053927-A1 | Heterocyclic Lipoxin Analogs and Uses Thereof | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2021-02-25 | — | — | US | disclosed |
| US-20210053927-A1 | Heterocyclic Lipoxin Analogs and Uses Thereof | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2021-02-25 | — | — | US | disclosed |
| EP-3500559-A1 | HETEROCYCLIC LIPOXON ANALOGS AND USES THEROF | University College Dublin (IE) | 2019-06-26 | — | — | EP | disclosed |
| WO-2018033642-A9 | HETEROCYCLIC LIPOXIN ANALOGS AND USES THEREOF | UNIVERSITY COLLEGE DUBLIN (IE) | 2018-10-18 | — | — | WO | disclosed |
| WO-2014184071-A1 | MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES | SYNGENTA LIMITED (GB) | 2014-11-20 | — | — | WO | disclosed |
| WO-2014184070-A1 | MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES | SYNGENTA LIMITED (GB) | 2014-11-20 | — | — | WO | disclosed |
| US-8188082-B2 | 5,6,7,8-tetrahydro-imidazo[1,5-α]pyrazine derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2012-05-29 | — | — | US | disclosed |
| EP-2420493-A1 | HALOALKYLSULFONANILIDE DERIVATIVE | Nissan Chemical Industries, Ltd. (JP) | 2012-02-22 | — | — | EP | disclosed |
| EP-2125823-B1 | 5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-02-15 | — | — | EP | disclosed |
| US-20120029187-A1 | HALOALKYLSULFONANILIDE DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-02-02 | — | — | US | disclosed |
| EP-2336104-A1 | ORTHO-SUBSTITUTED HALOALKYLSULFONANILIDE DERIVATIVE AND HERBICIDE | Nissan Chemical Industries, Ltd. (JP) | 2011-06-22 | — | — | EP | disclosed |
| US-20100093740-A1 | 5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD. (CH) | 2010-04-15 | — | — | US | disclosed |
| EP-2125823-A1 | 5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008078291-A1 | 5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11161824-B2 | Heterocyclic lipoxin analogs and uses thereof | LTB4R2, ALOX12, ALOX15B | ALDH1A1 1306/4885MAOB 382/4885AOC3 476/4885 |
| US-20100093740-A1 | 5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE DERIVATIVES | HCRTR1, HCRTR2, NPY5R | ALDH1A1 1460/4885MAOB 567/4885AOC3 255/4885 |
| US-20120029187-A1 | HALOALKYLSULFONANILIDE DERIVATIVE | CBR3, CBR1, HDHD5 | ALDH1A1 1574/4885MAOB 3755/4885AOC3 894/4885 |
| US-20210053927-A1 | Heterocyclic Lipoxin Analogs and Uses Thereof | LTB4R2, ALOX12, ALOX15B | ALDH1A1 1306/4885MAOB 382/4885AOC3 476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.