Sulfuric Acid

Sulfuric Acid

SCHEMBL5131260

C1CCOOC1.O=S(=O)(O)O

nearest known ligand 0.43

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA5A P35218 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
BLM P54132 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL8601317 1.00 CA5A (0.43) CA5ACA5BBLMKDM4E
Sulfuric Acid SCHEMBL8520468 0.97 CA5A (0.40) CA5ACA5B
Sulfuric Acid SCHEMBL16618110 0.97 CA5A (0.40) CA5ACA5B
Sulfuric Acid SCHEMBL4791378 0.94 CA5A (0.38) CA5ACA5B
Sulfuric Acid SCHEMBL11824871 0.93 CA5A (0.43) CA5ACA5BBLMKDM4E
Sulfuric Acid SCHEMBL2512992 0.89
Sulfuric Acid SCHEMBL17672948 0.85 CA5A (0.50) CA5ACA5BBLMKDM4E
Sulfuric Acid SCHEMBL13280458 0.82
Sulfuric Acid SCHEMBL2547472 0.80
Ether SCHEMBL10415713 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112062723-A Preparation method of thiabendazole intermediate 帕潘纳(北京)科技有限公司 2020-12-11 CN claimed
CN-112062723-B Preparation method of thiabendazole intermediate 帕潘纳(北京)科技有限公司 2022-03-25 CN disclosed
CN-111755735-B Porous organic compound electrolyte and preparation method and application thereof 中国科学院苏州纳米技术与纳米仿生研究所 2021-12-14 CN disclosed
CN-112062723-A Preparation method of thiabendazole intermediate 帕潘纳(北京)科技有限公司 2020-12-11 CN disclosed
CN-111755735-A Porous organic compound electrolyte and preparation method and application thereof 中国科学院苏州纳米技术与纳米仿生研究所 2020-10-09 CN disclosed
EP-2762485-B1 METHOD FOR PRODUCING POLYPEPTIDE FRAGMENT WITH HIGH EFFICIENCY, WHICH IS SUITABLE FOR NCL METHOD GLYTECH INC (JP) 2018-08-01 EP disclosed
EP-2684899-B1 METHOD FOR PRODUCING GLYCOPEPTIDE HAVING SIALYL SUGAR CHAIN, SIALYL SUGAR CHAIN-ADDED AMINO ACID DERIVATIVE TO BE USED IN SAME, AND GLYCOPEPTIDE GLYTECH INC (JP) 2018-04-25 EP disclosed
CN-103534276-B There is the manufacture method of the glycopeptide of sialic acid sugar chain, for the sialic acid sugar chain addition amino acid derivative of this manufacture method and this glycopeptide GLYTECH, INC. (JP) 2016-03-02 CN disclosed
US-9073978-B2 Method for producing glycopeptide having sialyl sugar chain, sialyl sugar chain-added amino acid derivative to be used in same, and glycopeptide GLYTECH, INC. (JP) 2015-07-07 US disclosed
US-20140377807-A1 METHOD FOR PRODUCING POLYPEPTIDE FRAGMENT WITH HIGH EFFICIENCY, WHICH IS SUITABLE FOR NCL METHOD GLYTECH, INC. (JP) 2014-12-25 US disclosed
CN-1237171-A Substituted benzocycloheptapyridine derivatives useful as farnesyl protein transferase inhibitors SCHERING CORP (US) 1999-12-01 CN disclosed
CN-1237165-A Tricyclic inhibitors of farnesyl protein transferase SCHERING CORP (US) 1999-12-01 CN disclosed
CN-1236364-A Substituted benzocycloheptapyridine derivatives useful for inhibition of Farnesyl protein transferase SCHERING CORP (US) 1999-11-24 CN disclosed
WO-1998049163-A1 COMPLEX COMPRISING A RARE-EARTH METAL ION AND A COMPLEXING MOIETY AKZO NOBEL N.V. (NL) 1998-11-05 WO disclosed
US-5770456-A Cyclic nucleic acid and polypeptide arrays AFFYMETRIX, INC. (US) 1998-06-23 US disclosed
WO-1997015566-A1 NOVEL OLIGOMERS, PROCESS FOR THEIR PREPARATION AND METHODS FOR THEIR USE GEORGHIOU PARIS E (CA) 1997-05-01 WO disclosed
US-5550215-A FORMING POLYMER ON SUBSTRATE WITH A TETHER MOLECULE; CYCLIZATION; DEPROTECTING; DECYCLIZATION AFFYMETRIX, INC. 1996-08-27 US disclosed
US-5527681-A Immobilized molecular synthesis of systematically substituted compounds AFFYMAX TECHNOLOGIES N.V. (NL) 1996-06-18 US disclosed
WO-1993010161-A1 POLYMER REVERSAL ON SOLID SURFACES AFFYMAX TECHNOLOGIES N.V. (AN) 1993-05-27 WO disclosed
US-4465567-A Process for the manufacture of 3-hydroxy-2-cycloalken-1-one derivatives HOFFMANN-LA ROCHE INC. (US) 1984-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140377807-A1 METHOD FOR PRODUCING POLYPEPTIDE FRAGMENT WITH HIGH EFFICIENCY, WHICH IS SUITABLE FOR NCL METHOD MET, NCLN, LNPEP CA5A 3601/4885CA5B 3130/4885BLM 3143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.