SCHEMBL513190

SCHEMBL513190

O=CCOc1cccc(SC(F)(F)F)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRZ1 P23471 2/20 0.38
CETP P11597 2/20 0.38
FFAR4 Q5NUL3 1/20 0.37
RXFP1 Q9HBX9 2/20 0.35
PTPN1 P18031 2/20 0.34
TRPV1 Q8NER1 3/20 0.33
MAOA P21397 3/20 0.33
MAOB P27338 3/20 0.33
LMNA P02545 2/20 0.33
BRAF P15056 2/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
PTPN2 P17706 1/20 0.32
PTPRB P23467 1/20 0.32
PTPN6 P29350 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12251503 0.79 TP53 (0.49) PTPRZ1CETPRXFP1MAOAMAOB
SCHEMBL514199 0.79 LMNA (0.35) PTPRZ1CETPFFAR4RXFP1PTPN1
SCHEMBL513189 0.78 PTPRZ1 (0.38) PTPRZ1CETPFFAR4RXFP1PTPN1
SCHEMBL1295715 0.77 FFAR4 (0.42) PTPRZ1CETPFFAR4RXFP1PTPN1
SCHEMBL12579981 0.76 MTNR1A (0.38) MAOAMAOBALDH1A1MAPT
SCHEMBL23163670 0.76 CHRM2 (0.47) CETPMAOB
SCHEMBL29705676 0.76 KDM4E (0.54) MAOBLMNAALDH1A1POLBL3MBTL1
SCHEMBL584635 0.76 KDM4E (0.54) MAOBLMNAALDH1A1POLBL3MBTL1
SCHEMBL29705642 0.76 CHRM2 (0.47) CETPMAOB
SCHEMBL1431541 0.73 MAOB (0.51) MAOAMAOBLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023210623-A1 HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME 株式会社エス・ディー・エス バイオテック 2023-11-02 WO disclosed
WO-2014184071-A1 MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES SYNGENTA LIMITED (GB) 2014-11-20 WO disclosed
WO-2014184070-A1 MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES SYNGENTA LIMITED (GB) 2014-11-20 WO disclosed
EP-2420493-A1 HALOALKYLSULFONANILIDE DERIVATIVE Nissan Chemical Industries, Ltd. (JP) 2012-02-22 EP disclosed
US-20120029187-A1 HALOALKYLSULFONANILIDE DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-02-02 US disclosed
EP-2336104-A1 ORTHO-SUBSTITUTED HALOALKYLSULFONANILIDE DERIVATIVE AND HERBICIDE Nissan Chemical Industries, Ltd. (JP) 2011-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029187-A1 HALOALKYLSULFONANILIDE DERIVATIVE CBR3, CBR1, HDHD5 PTPRZ1 477/4885CETP 4602/4885FFAR4 2918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.