SCHEMBL5132

SCHEMBL5132

CC(C)C1CCCCCCC1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.48
EPHX1 P07099 2/20 0.41
TP53 P04637 1/20 0.38
ALDH1A1 P00352 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CA12 O43570 2/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
MMP2 P08253 2/20 0.37
CA9 Q16790 2/20 0.37
KDM4E B2RXH2 1/20 0.36
GMNN O75496 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21575869 1.00 SHBG (0.48) SHBGEPHX1TP53ALDH1A1HSD17B10
SCHEMBL8022524 1.00 SHBG (0.48) SHBGEPHX1TP53ALDH1A1HSD17B10
SCHEMBL5282 1.00
SCHEMBL5412 1.00 SHBG (0.48) SHBGEPHX1TP53ALDH1A1HSD17B10
SCHEMBL3335831 1.00 SHBG (0.48) SHBGEPHX1TP53ALDH1A1HSD17B10
SCHEMBL28542817 1.00 SHBG (0.48) SHBGEPHX1TP53ALDH1A1HSD17B10
SCHEMBL7739164 1.00 SHBG (0.48) SHBGEPHX1TP53ALDH1A1HSD17B10
Cyclohexane SCHEMBL5321429 1.00 SHBG (0.48) SHBGEPHX1TP53ALDH1A1HSD17B10
Water SCHEMBL9224817 0.97 SHBG (0.46) SHBGEPHX1TP53ALDH1A1HSD17B10
SCHEMBL140725 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109647199-A A kind of preparation method of reverse osmosis membrane and thus obtained reverse osmosis membrane 时代沃顿科技有限公司 2019-04-19 CN claimed
CN-105694028-A Interfacial polymeric oil-phase reaction composition for preparing composite reverse osmosis membranes and use method thereof 贵阳时代沃顿科技有限公司 2016-06-22 CN claimed
WO-2023235880-A1 CD38 MODULATORS AND USES THEREOF AEOVIAN PHARMACEUTICALS, INC. (US) 2023-12-07 WO disclosed
WO-2023180237-A1 METHOD AND COMPOUND ATDBio Limited (GB) 2023-09-28 WO disclosed
US-20230295172-A1 COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS GILEAD SCIENCES, INC. 2023-09-21 US disclosed
US-11737349-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-22 US disclosed
US-11700765-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-11 US disclosed
CN-114682102-B Reverse osmosis membrane and preparation method thereof 沃顿科技股份有限公司 2023-06-27 CN disclosed
CN-114682102-A Reverse osmosis membrane and preparation method thereof 沃顿科技股份有限公司 2022-07-01 CN disclosed
CN-108440370-B Inhibitors of viral replication 鲁汶天主教大学 2021-07-30 CN disclosed
CN-112892249-A Polyamide reverse osmosis membrane and preparation method thereof 时代沃顿科技有限公司 2021-06-04 CN disclosed
US-5086071-A Improved chemical stability and ppotent in vivo TORAY INDUSTRIES, INC. (JP) 1992-02-04 US disclosed
EP-0232776-B1 2,5,6,7-TETRANOR-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES TORAY INDUSTRIES, INC. (JP) 1990-10-24 EP disclosed
EP-0389162-A1 2,5,6,7-Tetranor-4,8-inter-m-phenylene PGI2 derivatives TORAY INDUSTRIES, INC. (JP) 1990-09-26 EP disclosed
EP-0365678-A1 2,5,6,7-TETRANOR-4,8-INTER-m-PHENYLENE PGI 2 DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND USE THEREOF TORAY INDUSTRIES, INC. (JP) 1990-05-02 EP disclosed
US-4880939-A ANTISECRETORY AGENTS, HYPOTENSIVES, ANTICOAGULANTS TORAY INDUSTRIES (JP) 1989-11-14 US disclosed
US-4775692-A ANTILIPEMIC, ANTICOAGULANT, HYPOTENSIVE, ANTISECRETORY AND ANTIULCER AGENT TORAY INDUSTRIES, INC. (JP) 1988-10-04 US disclosed
EP-0274064-A2 2,5,6,7-Tetranor-18,18,19,19-tetradehydro-4,8-inter-m-phenylene PGI2 derivatives TORAY INDUSTRIES, INC. (JP) 1988-07-13 EP disclosed
EP-0232776-A2 2,5,6,7-tetranor-4,8-inter-m-phenylene PGI2 derivatives TORAY INDUSTRIES, INC. (JP) 1987-08-19 EP disclosed
US-3992451-A IN THE PRESENCE OF FREE RADICAL CATALYSTS, HYDROGEN CHLORIDE, AND CARBON MONOXIDE UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11737349-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OTC SHBG 2817/4885EPHX1 787/4885TP53 3701/4885
US-11700765-B2 Organic electroluminescent materials and devices SOD1, L1CAM, MCM2 SHBG 2620/4885EPHX1 528/4885TP53 3054/4885
US-20230295172-A1 COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS HAVCR2, EIF2AK2, OAT SHBG 2685/4885EPHX1 1218/4885TP53 186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.