Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL513376 | 0.90 | KDM4E (0.35) | BRD4BAZ2BLMNAPOLB | |
| SCHEMBL18797088 | 0.74 | BRD4 (0.47) | BRD4SMN1; SMN2 | |
| SCHEMBL10745343 | 0.74 | TNF (0.40) | TNFALDH1A1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL3258080 | 0.71 | ADORA3 (0.40) | TNFCUL4ATYMSALDH1A1SMN1; SMN2 | |
| SCHEMBL513275 | 0.71 | SMN1; SMN2 (0.38) | TNFCUL4AALDH1A1RXFP1SMN1; SMN2 | |
| SCHEMBL10918321 | 0.70 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2KMT2AL3MBTL1HPGD | |
| SCHEMBL9232485 | 0.69 | KMT2A (0.44) | TNFCUL4ATYMSALDH1A1BAZ2B | |
| SCHEMBL5983543 | 0.69 | ADORA2A (0.38) | TNFCUL4ATYMSALDH1A1HSD17B10 | |
| SCHEMBL4664835 | 0.69 | ADORA2A (0.44) | TNFCUL4ATYMSALDH1A1KMT2A | |
| SCHEMBL13611403 | 0.69 | CYP1A2 (0.51) | ALDH1A1BAZ2BBAZ2ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028988-A1 | USE OF PYRIDAZINONE COMPOUND FOR CONTROL OF HARMFUL ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028988-A1 | USE OF PYRIDAZINONE COMPOUND FOR CONTROL OF HARMFUL ARTHROPOD PESTS | PLPBP, PNPO, PIR | TNF 4277/4885CUL4A 981/4885BRD4 3219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.