Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL513375 | 0.81 | CDK8 (0.34) | SMN1; SMN2LMNAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL1517574 | 0.72 | MAPT (0.37) | SMN1; SMN2LMNAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL30080540 | 0.71 | LMNA (0.43) | SMN1; SMN2LMNAALDH1A1KDM4EPOLB | |
| SCHEMBL513276 | 0.71 | TNF (0.40) | SMN1; SMN2LMNAALDH1A1L3MBTL1CUL4A | |
| SCHEMBL9208273 | 0.69 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1NPSR1KDM4EL3MBTL1 | |
| SCHEMBL10918321 | 0.69 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1NPSR1SOAT1KDM4E | |
| SCHEMBL8142970 | 0.68 | ALDH1A1 (0.38) | SMN1; SMN2LMNAALDH1A1KDM4EPOLB | |
| Bicarbonate SCHEMBL513277 | 0.68 | CDK8 (0.37) | SMN1; SMN2LMNAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL393866 | 0.68 | TP53 (0.48) | SMN1; SMN2LMNAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL10915450 | 0.66 | PKM (0.47) | SMN1; SMN2LMNAALDH1A1POLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028988-A1 | USE OF PYRIDAZINONE COMPOUND FOR CONTROL OF HARMFUL ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028988-A1 | USE OF PYRIDAZINONE COMPOUND FOR CONTROL OF HARMFUL ARTHROPOD PESTS | PLPBP, PNPO, PIR | SMN1; SMN2 1710/4885LMNA 1748/4885ALDH1A1 1293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.