Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3841290 | 0.87 | ALDH1A1 (0.47) | FFAR1ALDH1A1MAPK1SLC6A2SLC6A4 | |
| SCHEMBL5139829 | 0.87 | HTR2C (0.42) | FFAR1SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL5131548 | 0.87 | HTR2C (0.42) | FFAR1SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL3881602 | 0.86 | MEN1 (0.43) | FFAR1ALDH1A1MAPK1CYP2D6PLA2G1B | |
| Hydrochloric Acid SCHEMBL3860311 | 0.86 | ALDH1A1 (0.47) | FFAR1ALDH1A1MAPK1SLC6A2SLC6A4 | |
| SCHEMBL3844268 | 0.84 | POLB (0.42) | FFAR1ALDH1A1MAPK1LMNA | |
| SCHEMBL3846301 | 0.84 | SCN9A (0.41) | ALDH1A1MAPK1MAPK14LMNA | |
| SCHEMBL3862104 | 0.84 | SCN9A (0.41) | ALDH1A1MAPK1MAPK14LMNA | |
| SCHEMBL3843530 | 0.83 | FFAR1 (0.46) | FFAR1EZH2ALDH1A1MAPK1CYP2D6 | |
| SCHEMBL3840556 | 0.83 | OPRK1 (0.42) | FFAR1ALDH1A1SLC6A2SLC6A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007136668-A9 | N-BENZOYL-AND N-BENZYLPYRROLIDIN-3-YLAMINES AS HISTAMINE-3 ANTAGONISTS | WYETH CORP (US) | 2008-03-27 | — | — | WO | claimed |