SCHEMBL5133319

SCHEMBL5133319

Bc1ccc2c(c1)Cc1cc(B)ccc1-2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.41
MAPT P10636 3/20 0.41
NPC1 O15118 2/20 0.41
LMNA P02545 2/20 0.41
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
HPGD P15428 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
CASP6 P55212 1/20 0.38
GFER P55789 1/20 0.38
SRD5A2 P31213 1/20 0.36
HSD17B1 P14061 1/20 0.35
CYP1A2 P05177 2/20 0.34
TLR9 Q9NR96 1/20 0.34
CYP3A4 P08684 1/20 0.34
KCNH2 Q12809 1/20 0.33
POLB P06746 1/20 0.33
ADRA2A P08913 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10070180 0.89 ALDH1A1 (0.59) RAB9AMAPTNPC1LMNAALDH1A1
SCHEMBL10045582 0.87 RAB9A (0.62) RAB9AMAPTNPC1LMNAALDH1A1
SCHEMBL14394729 0.87 METAP1 (0.47) RAB9AMAPTNPC1LMNAALDH1A1
SCHEMBL21841861 0.87 TDP2 (0.46) RAB9AMAPTNPC1LMNAALDH1A1
SCHEMBL10168271 0.87 METAP1 (0.47) RAB9AMAPTNPC1LMNAALDH1A1
SCHEMBL13070957 0.83 CASP1 (0.37) RAB9ANPC1SRD5A2HSD17B1MAOA
SCHEMBL22452308 0.82 NPC1 (0.32) RAB9AMAPTNPC1LMNAALDH1A1
SCHEMBL12219054 0.79 SMN1; SMN2 (0.53) RAB9AMAPTNPC1LMNAALDH1A1
SCHEMBL24730257 0.79 METAP1 (0.44) RAB9AMAPTNPC1LMNAALDH1A1
SCHEMBL10169203 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1475401-B1 Mono-, oligo- and polymers comprising fluorene and aryl groups MERCK PATENT GMBH (DE) 2009-05-27 EP disclosed
WO-2009017798-A1 CONJUGATED MONOMERS AND POLYMERS AND PREPARATION AND USE THEREOF NORTHWESTERN UNIVERSITY (US) 2009-02-05 WO disclosed
US-7442421-B2 Electroluminescent materials and methods of manufacture and use 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-10-28 US disclosed
US-20070237983-A1 ELECTROLUMINESCENT MATERIALS AND METHODS OF MANUFACTURE AND USE 3M INNOVATIVE PROPERTIES COMPANY 2007-10-11 US disclosed
US-7241512-B2 Light emitting polymers including a plurality of arylene monomeric units and a plurality of soft segment end caps, side chains and/or internal units 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-07-10 US disclosed
EP-1497393-A1 ELECTROLUMINESCENT MATERIALS AND METHODS OF MANUFACTURE AND USE 3M Innovative Properties Company (US) 2005-01-19 EP disclosed
US-20030224205-A1 Electroluminescent materials and methods of manufacture and use 3M INNOVATIVE PROPERTIES COMPANY 2003-12-04 US disclosed
WO-2003089542-A1 ELECTROLUMINESCENT MATERIALS AND METHODS OF MANUFACTURE AND USE 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-10-30 WO disclosed