SCHEMBL10070180

SCHEMBL10070180

Bc1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
NPC1 O15118 3/20 0.59
RAB9A P51151 3/20 0.59
MAPT P10636 2/20 0.59
HPGD P15428 2/20 0.59
KDM4E B2RXH2 2/20 0.59
LMNA P02545 2/20 0.59
SRD5A2 P31213 1/20 0.52
CYP1A2 P05177 5/20 0.49
CYP3A4 P08684 4/20 0.49
MAOA P21397 2/20 0.46
HTR2C P28335 2/20 0.46
HTR2B P41595 2/20 0.46
ADRA2A P08913 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
TSHR P16473 2/20 0.44
ATM Q13315 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12219054 0.91 SMN1; SMN2 (0.53) ALDH1A1SMN1; SMN2NPC1RAB9AMAPT
SCHEMBL5133319 0.89 RAB9A (0.41) ALDH1A1SMN1; SMN2NPC1RAB9AMAPT
SCHEMBL2720506 0.83 ALDH1A1 (0.70) ALDH1A1SMN1; SMN2NPC1RAB9AMAPT
SCHEMBL14026041 0.80 MAOA (0.67) ALDH1A1SMN1; SMN2NPC1RAB9AMAPT
SCHEMBL18582934 0.79 SMN1; SMN2 (0.64) ALDH1A1SMN1; SMN2NPC1RAB9AMAPT
SCHEMBL30912172 0.79 SMN1; SMN2 (0.64) ALDH1A1SMN1; SMN2NPC1RAB9AMAPT
SCHEMBL5058433 0.79 SMN1; SMN2 (0.64) ALDH1A1SMN1; SMN2NPC1RAB9AMAPT
SCHEMBL5016641 0.79 SMN1; SMN2 (0.64) ALDH1A1SMN1; SMN2NPC1RAB9AMAPT
SCHEMBL17067909 0.78 CES1 (0.46) ALDH1A1SMN1; SMN2NPC1RAB9AMAPT
Fluorene SCHEMBL8180 0.78 MAOA (0.68) ALDH1A1SMN1; SMN2NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4257586-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT-EMITTING DEVICE, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE LT Materials Co., Ltd. (KR) 2023-10-11 EP disclosed
EP-4242196-A1 METHOD FOR PREPARING DEUTERATED ANTHRACENE COMPOUND, REACTION COMPOSITION, DEUTERATED ANTHRACENE COMPOUND AND COMPOSITION Lg Chem, Ltd. (KR) 2023-09-13 EP disclosed
CN-115433217-B Carbazole-fused boron-nitrogen derivative and preparation method and application thereof 苏州大学 2023-08-25 CN disclosed
EP-4140990-A1 BENZO[B]NAPHTHO[2,1-D]FURAN COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME LT Materials Co., Ltd. (KR) 2023-03-01 EP disclosed
WO-2020188473-A1 SYNTHESIS OF METALLOCENE POLYMERIZATION CATALYST NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2020-09-24 WO disclosed
CN-104650090-B A kind of fluorene kind derivative of the bases of -3- containing carbazole group and its application 固安鼎材科技有限公司 2018-05-18 CN disclosed
US-9818958-B2 Biscarbazole derivatives and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2017-11-14 US disclosed
US-9786848-B2 Nanofiber-based heterojunction approach for high photoconductivity on organic materials UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2017-10-10 US disclosed
US-20160240795-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-08-18 US disclosed
US-9373802-B2 Biscarbazole derivatives and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2016-06-21 US disclosed
WO-2013013753-A2 POLYMERS AND OLIGOMERS WITH FUNCTIONALIZED SIDE GROUPS MERCK PATENT GMBH (DE) 2013-01-31 WO disclosed
EP-2551865-A2 Photoelectric conversion element and solar cell Konica Minolta Business Technologies, Inc. (JP) 2013-01-30 EP disclosed
US-20120223295-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE IDEMITSU KOSAN CO., LTD. (JP) 2012-09-06 US disclosed
US-20120100628-A1 EMISSIVE AND BROADBAND NONLINEAR ABSORBING METAL COMPLEXES AND LIGANDS AS OLED, OPTICAL SWITCHING OR OPTICAL SENSING MATERIALS NDSU RESEARCH FOUNDATION (US) 2012-04-26 US disclosed
WO-2011105700-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2011-09-01 WO disclosed
EP-2108690-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-10-14 EP disclosed
EP-2108689-A2 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-10-14 EP disclosed
EP-1475401-B1 Mono-, oligo- and polymers comprising fluorene and aryl groups MERCK PATENT GMBH (DE) 2009-05-27 EP disclosed
US-7521525-B2 Blue luminescent polymer and organoelectroluminescent device using the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2009-04-21 US disclosed
US-7425654-B2 Aromatic triamine compound and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2008-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120100628-A1 EMISSIVE AND BROADBAND NONLINEAR ABSORBING METAL COMPLEXES AND LIGANDS AS OLED, OPTICAL SWITCHING OR OPTICAL SENSING MATERIALS OCIAD2, OCIAD1, NONO ALDH1A1 3698/4885SMN1; SMN2 3850/4885NPC1 2581/4885
US-20120223295-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE EED, GABRE, EML4 ALDH1A1 543/4885SMN1; SMN2 4254/4885NPC1 4207/4885
US-20160240795-A1 BISCARBAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME EED, GABRE, EML4 ALDH1A1 412/4885SMN1; SMN2 4429/4885NPC1 4486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.