Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2931205 | 0.82 | L3MBTL1 (0.43) | L3MBTL1RORCMAPTKMT2AMEN1 | |
| SCHEMBL2926183 | 0.77 | L3MBTL1 (0.41) | L3MBTL1RORCMAPTKMT2AMEN1 | |
| SCHEMBL2927134 | 0.73 | ALDH1A1 (0.39) | L3MBTL1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL5133378 | 0.69 | MAPT (0.46) | RORCMAPTKMT2AMEN1POLB | |
| SCHEMBL29438429 | 0.68 | RAB9A (0.57) | L3MBTL1RORCMAPTKMT2AMEN1 | |
| SCHEMBL18167974 | 0.67 | L3MBTL1 (0.68) | L3MBTL1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL10710433 | 0.66 | RORC (0.61) | RORCMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL10743441 | 0.66 | RORC (0.61) | L3MBTL1RORCMAPTKMT2AMEN1 | |
| SCHEMBL1744194 | 0.65 | CHEK1 (0.45) | L3MBTL1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL10733809 | 0.64 | KMT2A (0.58) | L3MBTL1RORCMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987028-A2 | BENZAZOLE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE AS AURORA KINASE INHIBITORS | Transtech Pharma, Inc. (US) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007095124-A2 | BENZAZOLE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE AS AURORA KINASE INHIBITORS | TRANSTECH PHARMA, INC. (US) | 2007-08-23 | — | — | WO | disclosed |