Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31014187 | 0.84 | GPR35 (0.47) | RAB9ANPC1POLBNR3C2SMN1; SMN2 | |
| SCHEMBL31014185 | 0.84 | GPR35 (0.47) | RAB9ANPC1POLBNR3C2SMN1; SMN2 | |
| SCHEMBL4373422 | 0.84 | ALDH1A1 (0.53) | RAB9ANPC1POLBNR3C2SMN1; SMN2 | |
| SCHEMBL1979862 | 0.83 | ALDH1A1 (0.49) | RAB9ANPC1POLBSMN1; SMN2MEN1 | |
| SCHEMBL17707773 | 0.82 | LMNA (0.40) | RAB9ANPC1POLBNR3C2SMN1; SMN2 | |
| SCHEMBL28270666 | 0.80 | ITGB1 (0.38) | RAB9ANPC1POLBSMN1; SMN2MEN1 | |
| SCHEMBL17707769 | 0.79 | CRHBP (0.46) | RAB9ANPC1POLBSMN1; SMN2MEN1 | |
| SCHEMBL3785486 | 0.79 | TSHR (0.53) | POLBSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL31187277 | 0.79 | TSHR (0.45) | RAB9ANPC1NR3C2SMN1; SMN2MEN1 | |
| SCHEMBL4378724 | 0.79 | NR1D1 (0.39) | RAB9ANPC1POLBNR3C2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071411-B | Method for producing nitrobenzene compound | 组合化学工业株式会社 | 2021-08-27 | — | — | CN | disclosed |
| EP-3456705-B1 | METHOD FOR PRODUCING NITROBENZENE COMPOUND | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2020-12-16 | — | — | EP | disclosed |
| EP-3456705-A1 | METHOD FOR PRODUCING NITROBENZENE COMPOUND | Kumiai Chemical Industry Co., Ltd. (JP) | 2019-03-20 | — | — | EP | disclosed |
| EP-3015451-B1 | METHOD FOR PRODUCING NITROBENZENE COMPOUND | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2018-01-17 | — | — | EP | disclosed |
| EP-3015451-A1 | METHOD FOR MANUFACTURING NITROBENZENE COMPOUND | Ihara Chemical Industry Co., Ltd. (JP) | 2016-05-04 | — | — | EP | disclosed |
| EP-1999131-A2 | BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS | Nerviano Medical Sciences S.r.l. (IT) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007099171-A2 | BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2007-09-07 | — | — | WO | disclosed |