SCHEMBL5134065

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28091212	0.78	MEN1 (0.46)	MEN1KMT2AEGFRTLR7
	SCHEMBL5134062	0.78	OPRM1 (0.52)	ROCK1EGFRKDM4AKDM4BKDM5C
	SCHEMBL6469221	0.74	MEN1 (0.57)	MEN1KMT2AEGFRPOLBBACE1
	SCHEMBL28117672	0.74	ALDH1A1 (0.57)	MEN1KMT2ATDP1BCHEKDM4A
	SCHEMBL25375347	0.72	HTR1A (0.45)	MEN1KMT2ATDP1BCHEKDM4A
	SCHEMBL25376070	0.72	MEN1 (0.44)	MEN1KMT2ATDP1BCHEKDM4A
	SCHEMBL30482155	0.72	MEN1 (0.44)	MEN1KMT2ATDP1BCHEKDM4A
	SCHEMBL25373983	0.72	MEN1 (0.44)	MEN1KMT2ATDP1BCHEKDM4A
	SCHEMBL6469053	0.72	CASR (0.50)	MEN1KMT2ACYP1A2CYP2D6ALOX15
	SCHEMBL5799878	0.72	MEN1 (0.78)	MEN1KMT2ATDP1BCHEMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.