Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5134571 | 1.00 | MAOA (0.51) | MAOAMAOBRAB9AMEN1NPC1 | |
| SCHEMBL11429370 | 0.91 | CYP3A4 (0.57) | RAB9ANPC1ALDH1A1TP53CYP3A4 | |
| SCHEMBL28839751 | 0.86 | IDO1 (0.41) | MAOAMAOBRAB9AMEN1MAPT | |
| SCHEMBL10038879 | 0.86 | IDO1 (0.41) | MAOAMAOBRAB9AMEN1MAPT | |
| SCHEMBL9955019 | 0.85 | RELA (0.67) | MAOAMAOBRAB9AMAPTALDH1A1 | |
| SCHEMBL9955015 | 0.85 | RELA (0.67) | MAOAMAOBRAB9AMAPTALDH1A1 | |
| SCHEMBL22525324 | 0.83 | CYP1A1 (0.54) | RAB9AMEN1NPC1GAAMAPT | |
| SCHEMBL15105021 | 0.83 | TRPA1 (0.63) | MAOBRAB9AMEN1NPC1GAA | |
| SCHEMBL6680147 | 0.83 | ALDH1A1 (0.52) | MAOAMAOBRAB9AMEN1NPC1 | |
| SCHEMBL9954124 | 0.83 | TRPA1 (0.63) | MAOBRAB9AMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080146574-A1 | Heterocycle Substituted Carboxylic Acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY LLC | 2008-06-19 | — | — | US | disclosed |
| US-7329680-B2 | Heterocycle substituted carboxylic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2008-02-12 | — | — | US | disclosed |
| US-20060122222-A1 | Heterocycle substituted carboxylic acids | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC | 2006-06-08 | — | — | US | disclosed |
| US-20050004114-A1 | Heterocycle substituted carboxylic acids | INSTITUTE FOR DIABETES DISCOVERY, L.L.C. | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004114-A1 | Heterocycle substituted carboxylic acids | PTPRC, PTPRS, PTPRJ | MAOA 842/4885MAOB 378/4885RAB9A 2846/4885 |
| US-20080146574-A1 | Heterocycle Substituted Carboxylic Acids | PTPRC, PTPRS, PTPRJ | MAOA 842/4885MAOB 378/4885RAB9A 2846/4885 |
| US-20060122222-A1 | Heterocycle substituted carboxylic acids | PTPRC, PTPRS, PTPRJ | MAOA 842/4885MAOB 378/4885RAB9A 2846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.