Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL512734 | 0.79 | GPR119 (0.31) | — | |
| SCHEMBL11034475 | 0.76 | PTPRB (0.34) | PTPRB | |
| SCHEMBL514330 | 0.70 | NPC1 (0.46) | — | |
| SCHEMBL513297 | 0.70 | — | — | |
| SCHEMBL15116412 | 0.68 | LMNA (0.33) | PTPRB | |
| SCHEMBL9863815 | 0.68 | MAPT (0.37) | — | |
| SCHEMBL6820625 | 0.68 | POLB (0.41) | CNR2 | |
| SCHEMBL11034468 | 0.67 | KDM1A (0.34) | — | |
| SCHEMBL11764105 | 0.66 | FDPS (0.39) | — | |
| SCHEMBL11763139 | 0.65 | FDPS (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028931-A1 | HETEROCYCLIC M-GLU5 ANTAGONISTS | RECORDATI IRELAND LIMITED (IE) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028931-A1 | HETEROCYCLIC M-GLU5 ANTAGONISTS | OPRM1, GRM5, OPRD1 | PTPRB 4303/4885CNR2 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.