Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5134854 | 0.78 | CNR1 (0.37) | OPRL1POLBKCNH2CNR1CNR2 | |
| SCHEMBL5332673 | 0.76 | CNR1 (0.33) | OPRM1OPRL1OPRD1POLBCYP2D6 | |
| SCHEMBL1290783 | 0.72 | OPRM1 (0.35) | OPRM1OPRL1 | |
| SCHEMBL22122901 | 0.72 | POLB (0.47) | POLBMAPT | |
| SCHEMBL17185047 | 0.68 | SLC6A4 (0.56) | OPRD1MAPTCYP2D6KCNH2SLC6A2 | |
| SCHEMBL30644811 | 0.67 | NSD2 (0.49) | POLBMAPT | |
| SCHEMBL29845665 | 0.67 | NSD2 (0.49) | POLBMAPT | |
| SCHEMBL30804747 | 0.67 | TGFBR1 (0.49) | — | |
| SCHEMBL30731030 | 0.66 | USP30 (0.51) | OPRM1OPRD1OPRK1 | |
| SCHEMBL250597 | 0.64 | ACHE (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942893-A2 | PIPERIDINE GLYCINE TRANSPORTER INHIBITORS | Merck & Co., Inc. (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007053400-A2 | PIPERIDINE GLYCINE TRANSPORTER INHIBITORS | MERCK & CO., INC. (US) | 2007-05-10 | — | — | WO | disclosed |