SCHEMBL5136550

SCHEMBL5136550

Clc1cc(C2CCCCC2)c(Cl)c(Cl)c1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.42
CEL P19835 2/20 0.39
HSP90AA1 P07900 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
PTGDR2 Q9Y5Y4 7/20 0.34
PTGDR Q13258 4/20 0.34
PTGER2 P43116 1/20 0.34
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
CYP2D6 P10635 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
KCNH2 Q12809 1/20 0.33
TDO2 P48775 1/20 0.33
SIGMAR1 Q99720 2/20 0.33
TMEM97 Q5BJF2 1/20 0.33
EBP Q15125 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68378 0.71 HSP90AA1 (0.44) CELHSP90AA1HPGDTSHRHSD17B10
SCHEMBL15243172 0.70 TDO2 (0.43) CELHSP90AA1TDO2
SCHEMBL3783301 0.68 CEL (0.50) CELHSP90AA1PTGDR2PTGDRPTGER2
SCHEMBL15565267 0.68 ALDH1A1 (0.50) CYP3A4HPGDTSHRHSD17B10CHRNB2
SCHEMBL28492820 0.68 SLC6A9 (0.40) CELPTGDR2PTGDRPTGER2
SCHEMBL24069104 0.68 CEL (0.46) CELTSHRSLC6A2SLC6A4SLC6A3
SCHEMBL9485492 0.68 OPRL1 (0.42) CELHSP90AA1PTGDR2PTGDRPTGER2
SCHEMBL434608 0.68 GAA (0.56) CELTSHRPTGDR2PTGDRPTGER2
SCHEMBL126651 0.68 CEL (0.46) CELTSHRSLC6A2SLC6A4SLC6A3
SCHEMBL126782 0.68 PTGDR2 (0.50) CELTSHRPTGDR2PTGDRPTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1996538-A1 METHOD FOR PREPARATION OF AROMATIC CHLOROFORMATES Sabic Innovative Plastics IP B.V. (NL) 2008-12-03 EP disclosed
WO-2007001757-A1 METHOD FOR PREPARATION OF AROMATIC CHLOROFORMATES GENERAL ELECTRIC COMPANY (US) 2007-01-04 WO disclosed