Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 4/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2045161 | 0.77 | SPHK1 (0.36) | — | |
| SCHEMBL1128876 | 0.69 | SORT1 (0.32) | SORT1 | |
| SCHEMBL25591059 | 0.64 | CNR2 (0.36) | HTR1A | |
| SCHEMBL1129421 | 0.64 | ALDH1A1 (0.35) | SORT1 | |
| SCHEMBL16187110 | 0.63 | HTR1D (0.35) | — | |
| SCHEMBL12952917 | 0.62 | — | — | |
| SCHEMBL4562583 | 0.62 | — | — | |
| SCHEMBL26946141 | 0.62 | GABRA1 (0.30) | — | |
| SCHEMBL27346981 | 0.62 | NOS3 (0.37) | SORT1 | |
| SCHEMBL13312286 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072077-A2 | COMBINATION OF 1-ARYL-4-CYCLOPROPYLPYRAZOLES WITH ANTHELMINTIC AGENT FOR PARASITIC INFESTATION | PFIZER LIMITED (GB) | 2008-06-19 | — | — | WO | disclosed |