Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15995061 | 0.81 | KDM4E (0.34) | — | |
| SCHEMBL2040371 | 0.79 | LIPG (0.35) | — | |
| SCHEMBL16058495 | 0.75 | LPL (0.31) | — | |
| SCHEMBL5138610 | 0.69 | ADRA2A (0.34) | SORT1 | |
| SCHEMBL22091090 | 0.67 | — | — | |
| SCHEMBL1129421 | 0.66 | ALDH1A1 (0.35) | SORT1 | |
| SCHEMBL578136 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL13279832 | 0.62 | LMNA (0.31) | — | |
| SCHEMBL18858518 | 0.61 | TLR7 (0.37) | SORT1NOS3NOS1NOS2 | |
| SCHEMBL29317119 | 0.60 | NOS3 (0.40) | SORT1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282742-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | Infinity Pharmaceuticals, Inc. (US) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009126691-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC (US) | 2009-10-15 | — | — | WO | disclosed |