Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5140282 | 0.76 | PIK3CD (0.44) | ALDH1A1LMNAGSK3BPRKDCPIK3CD | |
| SCHEMBL27536636 | 0.76 | ALDH1A1 (0.56) | ALDH1A1LMNAGSK3BPRKDCMAPT | |
| SCHEMBL11951500 | 0.72 | MAOB (0.60) | ALDH1A1LMNAGSK3BMAPTMEN1 | |
| SCHEMBL23053215 | 0.72 | ALDH1A1 (0.49) | ALDH1A1LMNAGSK3BPRKDCMAPT | |
| SCHEMBL11061699 | 0.72 | ALDH1A1 (0.49) | ALDH1A1LMNAGSK3BPRKDCMAPT | |
| SCHEMBL3158614 | 0.72 | LMNA (0.52) | ALDH1A1LMNAGSK3BPRKDCPIK3CD | |
| SCHEMBL18212293 | 0.72 | LMNA (0.52) | ALDH1A1LMNAGSK3BPRKDCPIK3CD | |
| SCHEMBL27811257 | 0.72 | GSK3B (0.56) | ALDH1A1LMNAGSK3BPRKDCMAPT | |
| SCHEMBL6383636 | 0.71 | ALDH1A1 (0.50) | ALDH1A1LMNAGSK3BPRKDCPIK3CD | |
| SCHEMBL5217443 | 0.71 | ALDH1A1 (0.55) | ALDH1A1LMNAGSK3BPRKDCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080045708-A1 | New Process for the Synthesis of Morpholinylbenzenes | TIAN WEI | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045708-A1 | New Process for the Synthesis of Morpholinylbenzenes | CYP1B1, TBCB, MAP1B | ALDH1A1 2203/4885LMNA 1456/4885GSK3B 3241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.