SCHEMBL5142200

SCHEMBL5142200

C=Cc1ccc(CC(C(=O)O)C(=O)OC(C)(C)C)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 2/20 0.43
ITGA4 P13612 1/20 0.38
ITGB7 P26010 1/20 0.38
PPARG P37231 3/20 0.36
PPARD Q03181 2/20 0.36
PPARA Q07869 2/20 0.36
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
SLC7A5 Q01650 1/20 0.36
ITGB3 P05106 1/20 0.36
ITGA2B P08514 1/20 0.36
ATM Q13315 1/20 0.35
CTSS P25774 4/20 0.35
CTSK P43235 4/20 0.35
ACE P12821 1/20 0.35
KLK5 Q9Y337 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MIF P14174 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26907964 0.90 LDHA (0.36) LDHAITGA4ITGB7TAS1R3TAS1R1
SCHEMBL13101215 0.87 LDHA (0.42) LDHAPPARGPPARATAS1R3TAS1R1
SCHEMBL5145949 0.86 CTSB (0.42) ITGA4ITGB7PPARAATMPOLB
SCHEMBL5146853 0.82 PPARG (0.38) LDHAPPARGPPARDPPARAATM
SCHEMBL28857324 0.82 LDHA (0.47) LDHAITGA4ITGB7PPARGPPARD
SCHEMBL8119032 0.82 CTSS (0.49) LDHAITGA4ITGB7SLC7A5CTSS
SCHEMBL4909735 0.82 ITGA4 (0.51) LDHAITGA4ITGB7SLC7A5ATM
SCHEMBL1595565 0.82 ITGA4 (0.51) LDHAITGA4ITGB7SLC7A5ATM
SCHEMBL1595571 0.82 ITGA4 (0.51) LDHAITGA4ITGB7SLC7A5ATM
SCHEMBL5146874 0.81 LDHA (0.52) LDHAPPARGPPARDTAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8362106-B2 Decarboxylating block copolymers E I DU PONT DE NEMOURS AND COMPANY (US) 2013-01-29 US disclosed
US-8362106-B2 Decarboxylating block copolymers E I DU PONT DE NEMOURS AND COMPANY (US) 2013-01-29 US disclosed
EP-1240552-B1 WATER-PROCESSABLE PHOTORESIST COMPOSITIONS INTELLECTUAL VENTURES HOLDING 40 LLC (US) 2012-09-19 EP disclosed
US-20100273931-A1 DECARBOXYLATING BLOCK COPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-10-28 US disclosed
WO-2009073702-A1 DECARBOXYLATING BLOCK COPOLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-11 WO disclosed
EP-1240552-A4 WATER-PROCESSABLE PHOTORESIST COMPOSITIONS UNIV TEXAS (US) 2007-10-17 EP disclosed
EP-1240552-A1 WATER-PROCESSABLE PHOTORESIST COMPOSITIONS Board of Regents, The University of Texas System (US) 2002-09-18 EP disclosed
US-6399273-B1 Water-processable photoresist compositions BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM 2002-06-04 US disclosed
WO-2001013179-A1 WATER-PROCESSABLE PHOTORESIST COMPOSITIONS BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) 2001-02-22 WO disclosed