SCHEMBL5146853

SCHEMBL5146853

C=Cc1ccc(CC(C(=O)O)C(=O)OC(C)(C)CCc2ccccc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPARG P37231 8/20 0.38
PPARA Q07869 7/20 0.38
MMP8 P22894 1/20 0.36
PPARD Q03181 1/20 0.36
SRR Q9GZT4 2/20 0.36
LDHA P00338 1/20 0.36
NOS2 P35228 3/20 0.35
NOS3 P29474 2/20 0.35
NOS1 P29475 2/20 0.35
AKR1B10 O60218 2/20 0.35
AKR1B1 P15121 2/20 0.35
MAOB P27338 1/20 0.35
ATM Q13315 1/20 0.35
MIF P14174 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5142200 0.82 LDHA (0.43) PPARGPPARAPPARDLDHAATM
SCHEMBL5145949 0.78 CTSB (0.42) PPARAMMP8ATMMIF
SCHEMBL5144190 0.77 MMP8 (0.38) PPARGPPARAMMP8
SCHEMBL5144290 0.74 NAAA (0.43) PPARGPPARA
SCHEMBL3504292 0.74 NAAA (0.44)
SCHEMBL26907964 0.74 LDHA (0.36) LDHAATMMIF
SCHEMBL13101215 0.74 LDHA (0.42) PPARGPPARALDHAATM
SCHEMBL4909735 0.74 ITGA4 (0.51) MMP8SRRLDHAATM
SCHEMBL1595565 0.74 ITGA4 (0.51) MMP8SRRLDHAATM
SCHEMBL1595571 0.74 ITGA4 (0.51) MMP8SRRLDHAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1240552-B1 WATER-PROCESSABLE PHOTORESIST COMPOSITIONS INTELLECTUAL VENTURES HOLDING 40 LLC (US) 2012-09-19 EP disclosed
EP-1240552-A4 WATER-PROCESSABLE PHOTORESIST COMPOSITIONS UNIV TEXAS (US) 2007-10-17 EP disclosed
EP-1240552-A1 WATER-PROCESSABLE PHOTORESIST COMPOSITIONS Board of Regents, The University of Texas System (US) 2002-09-18 EP disclosed
US-6399273-B1 Water-processable photoresist compositions BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM 2002-06-04 US disclosed
WO-2001013179-A1 WATER-PROCESSABLE PHOTORESIST COMPOSITIONS BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) 2001-02-22 WO disclosed