SCHEMBL5142659

SCHEMBL5142659

CC(C)CN1CCCCC1C(C)N

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
PIK3CD O00329 1/20 0.31
SLC6A9 P48067 1/20 0.30
MAPT P10636 1/20 0.30
ALDH1A1 P00352 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2167980 0.81 CNR1 (0.35) CNR1CNR2PIK3CDSLC6A9MAPT
SCHEMBL13416610 0.78 SLC6A9 (0.38) PIK3CDSLC6A9
SCHEMBL18199163 0.78 SLC6A9 (0.38) PIK3CDSLC6A9
SCHEMBL3535268 0.76 L3MBTL1 (0.38) ALDH1A1
SCHEMBL4038087 0.76 L3MBTL1 (0.38) ALDH1A1
SCHEMBL4035789 0.76 L3MBTL1 (0.38) ALDH1A1
SCHEMBL4808864 0.74 HTT (0.35) CNR1CNR2PIK3CD
SCHEMBL4597568 0.74 HTT (0.35) CNR1CNR2PIK3CD
Ammonia Solution, Strong SCHEMBL9243093 0.74 L3MBTL1 (0.37) ALDH1A1
Formic Acid SCHEMBL28358042 0.74 CNR1 (0.34) CNR1CNR2SLC6A9MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7301022-B2 Vanilloid receptor ligands and their use in treatments AMGEN INC. (US) 2007-11-27 US disclosed
US-20060183745-A1 Vanilloid receptor ligands and their use in treatments AMGEN INC. 2006-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060183745-A1 Vanilloid receptor ligands and their use in treatments TRPV1, TRPV2, TRPV3 CNR1 391/4885CNR2 171/4885PIK3CD 3145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.