Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514087 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHRKMT2AMGLL | |
| SCHEMBL14433301 | 0.95 | MGLL (0.38) | ALDH1A1TSHRKMT2AMGLL | |
| SCHEMBL514401 | 0.94 | CTSL (0.31) | — | |
| SCHEMBL20853810 | 0.94 | CTSL (0.31) | — | |
| SCHEMBL514846 | 0.94 | MGLL (0.33) | MGLL | |
| SCHEMBL11219356 | 0.89 | MGLL (0.31) | MGLL | |
| SCHEMBL10926074 | 0.89 | MGLL (0.40) | ALDH1A1TSHRKMT2AMGLL | |
| SCHEMBL20853812 | 0.89 | — | — | |
| SCHEMBL19474824 | 0.89 | MGLL (0.40) | ALDH1A1TSHRKMT2AMGLL | |
| SCHEMBL19593693 | 0.89 | MGLL (0.40) | ALDH1A1TSHRKMT2AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9849196-B2 | Methods and compositions for altering photophysical properties of fluorophores via proximal quenching | CORNELL UNIVERSITY (US) | 2017-12-26 | — | — | US | disclosed |
| US-9631096-B2 | Dye compositions, methods of preparation, conjugates thereof, and methods of use | CORNELL UNIVERSITY (US) | 2017-04-25 | — | — | US | disclosed |
| US-20150328340-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERTIES OF FLUOROPHORES VIA PROXIMAL QUENCHING | CORNELL UNIVERSITY (US) | 2015-11-19 | — | — | US | disclosed |
| US-8945515-B2 | Methods and compositions for altering photophysical properties of fluorophores via proximal quenching | CORNELL UNIVERSITY (US) | 2015-02-03 | — | — | US | disclosed |
| US-20150011731-A1 | DYE COMPOSITIONS, METHODS OF PREPARATION, CONJUGATES THEREOF, AND METHODS OF USE | CORNELL UNIVERSITY (US) | 2015-01-08 | — | — | US | disclosed |
| WO-2013109859-A1 | DYE COMPOSITIONS, METHODS OF PREPARATION, CONJUGATES THEREOF, AND METHODS OF USE | CORNELL UNIVERSITY (US) | 2013-07-25 | — | — | WO | disclosed |
| US-20120027689-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERITES OF FLUOROPHORES VIA PROXIMAL QUENCHING | CORNELL UNIVERSITY (US) | 2012-02-02 | — | — | US | disclosed |
| US-7531298-B2 | Silver halide color photosensitive material | FUJIFILM CORPORATION (JP) | 2009-05-12 | — | — | US | disclosed |
| US-7531298-B2 | Silver halide color photosensitive material | FUJIFILM CORPORATION (JP) | 2009-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027689-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERITES OF FLUOROPHORES VIA PROXIMAL QUENCHING | APEX1, PPOX, PRDX5 | ALDH1A1 525/4885TSHR 4483/4885KMT2A 3610/4885 |
| US-20150328340-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERTIES OF FLUOROPHORES VIA PROXIMAL QUENCHING | APEX1, ARFGEF1, PRDX3 | ALDH1A1 800/4885TSHR 4051/4885KMT2A 3737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.