Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.58 |
| ▸ | SRC | P12931 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.38 |
| ▸ | TUBB | P07437 | 2/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5767867 | 0.79 | EGFR (0.52) | EGFRSRCKDM4EFNTAFNTB | |
| SCHEMBL28012374 | 0.78 | ALDH1A1 (0.49) | EGFRSRCKDM4EMAPTATM | |
| SCHEMBL7127234 | 0.78 | EGFR (0.63) | EGFRSRCKDM4EMAPTALDH1A1 | |
| SCHEMBL29915686 | 0.78 | EGFR (0.63) | EGFRSRCKDM4EMAPTALDH1A1 | |
| SCHEMBL3868019 | 0.75 | MAPT (0.65) | EGFRKDM4EMAPTATMALDH1A1 | |
| SCHEMBL29128851 | 0.75 | HTR6 (0.52) | EGFRSRCKDM4EMAPTATM | |
| SCHEMBL3221608 | 0.75 | EGFR (0.59) | EGFRSRCKDM4EFNTAFNTB | |
| SCHEMBL9503673 | 0.75 | KDM4E (0.52) | EGFRSRCKDM4EMAPTALDH1A1 | |
| SCHEMBL6669729 | 0.75 | EGFR (0.63) | EGFRSRCKDM4EFNTAFNTB | |
| SCHEMBL5571976 | 0.75 | KDM4E (0.48) | KDM4EMAPTATMALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499188-A4 | TOBACCO HAVING REDUCED NICOTINE AND NITROSAMINES | VECTOR TOBACCO LTD (BM) | 2007-11-14 | — | — | EP | disclosed |
| EP-1499188-A1 | TOBACCO HAVING REDUCED NICOTINE AND NITROSAMINES | Vector Tobacco Ltd. (BM) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003086076-A1 | TOBACCO HAVING REDUCED NICOTINE AND NITROSAMINES | VECTOR TOBACCO LTD. (BM) | 2003-10-23 | — | — | WO | disclosed |