SCHEMBL514455

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL248077	0.80	LMNA (0.59)	LMNACYP1A2CYP3A4MAOATSHR
	SCHEMBL6228872	0.80	LMNA (0.59)	LMNACYP1A2CYP3A4MAOATSHR
	SCHEMBL7349441	0.78	TSHR (0.60)	TSHRMAPTALDH1A1
	SCHEMBL8315092	0.78	CA1 (0.60)	LMNACYP1A2TSHRCYP2C19MAPT
	SCHEMBL1000847	0.78	LMNA (0.57)	LMNACYP1A2CYP3A4MAOATSHR
	SCHEMBL5953546	0.78	LMNA (0.57)	LMNACYP1A2CYP3A4MAOATSHR
	SCHEMBL514973	0.77	LMNA (0.61)	LMNACYP1A2CYP3A4MAOATSHR
	SCHEMBL513954	0.76	TDP1 (0.64)	LMNACYP1A2NPC1RAB9AMAPT
	SCHEMBL16592065	0.76	LMNA (0.55)	LMNACYP1A2CYP3A4MAOATSHR
	SCHEMBL556622	0.76	CES2 (0.54)	CYP1A2NPC1RAB9AMAPTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.